Versatile synthetic platform for 1, 2, 3-triazole chemistry

DP Vala, RM Vala, HM Patel - Acs Omega, 2022 - ACS Publications
1, 2, 3-Triazole scaffolds are not obtained in nature, but they are still intensely investigated
by synthetic chemists in various fields due to their excellent properties and green synthetic …

Benzimidazole-triazole hybrids as antimicrobial and antiviral agents: A systematic review

M Marinescu - Antibiotics, 2023 - mdpi.com
Bacterial infections have attracted the attention of researchers in recent decades, especially
due to the special problems they have faced, such as their increasing diversity and …

A review on the green synthesis of benzimidazole derivatives and their pharmacological activities

M Nardi, NCH Cano, S Simeonov, R Bence, A Kurutos… - Catalysts, 2023 - mdpi.com
Benzimidazoles and their derivatives play an extraordinarily significant role as therapeutic
agents, eg, antiulcer, analgesic, and anthelmintic drugs. The organic synthesis of …

Perspectives of benzimidazole derivatives as anticancer agents in the new era

S Yadav, B Narasimhan - Anti-Cancer Agents in Medicinal …, 2016 - ingentaconnect.com
Cancer is one of the deadliest diseases nowadays and is a great topic for research as the
challenging task is to develop new entities with selectivity towards cancerous cells …

Autofluorescent Artemisinin‐Benzimidazole Hybrids via Organo‐Click Reaction: Study of Antiviral Properties and Mode of Action in Living Cells

L Herrmann, F Hahn, BW Grau, M Wild… - … A European Journal, 2023 - Wiley Online Library
Drug modification by a fluorescent label is a common tool for studying its mechanism of
action with fluorescence microscopy techniques. However, the attachment of a fluorescent …

Synthesis and biological evaluation of substituted N-(2-(1H-benzo [d] imidazol-2-yl) phenyl) cinnamides as tubulin polymerization inhibitors

K Donthiboina, P Anchi, S Gurram, GS Mani… - Bioorganic …, 2020 - Elsevier
A new series of N-(2-(1H-benzo [d] imidazol-2-yl) phenyl) cinnamides was prepared and
evaluated for their in vitro cytotoxic activity using various cancer cell lines viz. A549 (human …

Benzimidazole-1, 2, 3-triazole hybrid molecules: Synthesis and study of their interaction with G-quadruplex DNA

PS Singu, U Chilakamarthi, NS Mahadik… - RSC Medicinal …, 2021 - pubs.rsc.org
A series of new benzimidazole-1, 2, 3-triazole hybrid derivatives have been synthesized via
'click'reaction and evaluated for their in vitro cytotoxicity as well as DNA binding affinity. MTT …

1, 2, 3-Triazoles based 3-substituted 2-thioquinoxalines: Synthesis, anti-bacterial activities, and molecular docking studies

A Keivanloo, M Fakharian, S Sepehri - Journal of Molecular Structure, 2020 - Elsevier
Abstract New 1, 2, 3-triazoles based on 3-Substituted 2-thioquinoxalines were synthesized
via a copper-catalyzed click reaction. The new 1, 2, 3-triazoles were screened for their in …

Benzimidazole ring system as a privileged template for anticancer agents

A Kanwal, FA Saddique, S Aslam, M Ahmad… - Pharmaceutical …, 2018 - Springer
Cancer still remains a continued threat for human race in the 21st century. It is the major
cause of human casualties globally and is thus, a hot topic of research in medicinal …

Solvent-free synthesis and anticancer activity evaluation of benzimidazole and perimidine derivatives

A Kumar, S Banerjee, P Roy, SM Sondhi, A Sharma - Molecular Diversity, 2018 - Springer
Benzimidazoles and perimidines are subsidiary structures for research and development of
new biologically active molecules and have established prominence because of their …