Insight into the potential mechanisms of endocrine disruption by Dietary Phytoestrogens in the context of the etiopathogenesis of endometriosis

D Szukiewicz - International Journal of Molecular Sciences, 2023 - mdpi.com
Phytoestrogens (PEs) are estrogen-like nonsteroidal compounds derived from plants (eg,
nuts, seeds, fruits, and vegetables) and fungi that are structurally similar to 17β-estradiol …

Endometriosis and the role of pro-inflammatory and anti-inflammatory cytokines in pathophysiology: a narrative review of the literature

IE Oală, MI Mitranovici, DM Chiorean, T Irimia… - Diagnostics, 2024 - mdpi.com
Endometriosis is a chronic inflammatory disease, which explains the pain that such patients
report. Currently, we are faced with ineffective, non-invasive diagnostic methods and …

Single-cell transcriptome analysis reveals endometrial immune microenvironment in minimal/mild endometriosis

X Huang, L Wu, T Pei, D Liu, C Liu, B Luo… - Clinical and …, 2023 - academic.oup.com
Endometriosis is a common inflammatory disorder in women of reproductive age due to an
abnormal endometrial immune environment and is associated with infertility. This study …

GPR30-mediated non-classic estrogen pathway in mast cells participates in endometriosis pain via the production of FGF2

X Xu, J Wang, X Guo, Y Chen, S Ding, G Zou… - Frontiers in …, 2023 - frontiersin.org
Pain is one of the main clinical symptoms of endometriosis, but its underlying mechanism is
still not clear. Recent studies have shown that the secretory mediators of mast cells activated …

Mast cell tryptase and carboxypeptidase A3 in the formation of ovarian endometrioid cysts

D Atiakshin, O Patsap, A Kostin, L Mikhalyova… - International Journal of …, 2023 - mdpi.com
The mechanisms of ovarian endometrioid cyst formation, or cystic ovarian endometriosis,
still remain to be elucidated. To address this issue, we analyzed the involvement of mast cell …

[HTML][HTML] The role of peritoneal immunity in peritoneal endometriosis and related infertility

Q Huang, Y Yu, W Xu, S Li, Y Zhou… - Frontiers in Bioscience …, 2023 - imrpress.com
Endometriosis is defined as a disorder in which the glands and stroma of the endometrium
grow and shed periodically outside the uterine cavity. Highly prevalent in women of …

[HTML][HTML] The Estrogen–Immune Interface in Endometriosis

E Greygoose, P Metharom, H Kula, TK Seckin… - Cells, 2025 - mdpi.com
Endometriosis is a gynecologic condition characterized by the growth of endometrium-like
stroma and glandular elements outside of the uterine cavity. The involvement of hormonal …

The Dysregulated IL-23/TH17 Axis in Endometriosis Pathophysiology

DJ Sisnett, KB Zutautas, JE Miller… - The Journal of …, 2024 - journals.aai.org
Endometriosis is a chronic inflammatory disease in which endometrial-like tissue grows
ectopically, resulting in pelvic pain and infertility. IL-23 is a key contributor in the …

[HTML][HTML] Dietary and Nutritional Interventions for the Management of Endometriosis

N Abulughod, S Valakas, F El-Assaad - Nutrients, 2024 - mdpi.com
Endometriosis is a chronic, complex, systemic inflammatory condition that impacts
approximately 190 million girls and women worldwide, significantly impacting their quality of …

Landscape of Endometrial Cancer: Molecular Mechanisms, Biomarkers, and Target Therapy

IS Bostan, M Mihaila, V Roman, N Radu, MT Neagu… - Cancers, 2024 - mdpi.com
Simple Summary Endometrial cancer is a complex disease with multiple risk factors, distinct
histological subtypes, and a variety of available therapeutic options. The disease's …