Background As the population ages, increasing numbers of older adults are undergoing
surgery. Frailty is prevalent in older adults and may be a better predictor of post-operative …

Frailty is a multidimensional syndrome characterized by decreased reserve and diminished
resistance to stressors. People with frailty are vulnerable to stressors, and exposure to the …

Background Frailty is a geriatric syndrome that diminishes the potential for functional
recovery after a transcatheter aortic valve replacement (TAVR) or surgical aortic valve …

Aims In patients with aortic stenosis (AS), risk stratification for aortic valve replacement
(AVR) relies mainly on valve-related factors, symptoms and co-morbidities. We sought to …

Aims Based on randomized trials using first-generation devices, transcatheter aortic valve
replacement (TAVR) is well established in the treatment of high-risk (HR) patients with …

Transcatheter aortic valve implantation (TAVI) has spawned the evolution of novel catheter-
based therapies for a variety of cardiovascular conditions. Newer device iterations are …

Frailty is a geriatric syndrome characterised by a vulnerability status associated with
declining function of multiple physiological systems and loss of physiological reserves. Two …

Background: Frailty assessment may inform surgical risk and prognosis not captured by
conventional surgical risk scores. Purpose: To evaluate the evidence for various frailty …

Registry data that shows a clinically meaningful association of higher mortality and other
major complications with site annual volume below the recommended threshold of 50 …

Frailty is an age-associated clinical syndrome characterized by a decrease in physiological
reserve in situations of stress, constituting a state of vulnerability that involves a higher risk of …