Exploring dendrimer-based drug delivery systems and their potential applications in cancer immunotherapy

S Mukherjee, S Mukherjee, MAS Abourehab… - European Polymer …, 2022 - Elsevier
Cancer immunotherapy has been researched as a major modality of treatment which
involves activating the immune system of the patient to fight against tumor cells. Dendrimers …

Biocatalyzed synthesis of glycostructures with anti-infective activity

P Hoyos, A Perona, T Bavaro, F Berini… - Accounts of Chemical …, 2022 - ACS Publications
Conspectus Molecules containing carbohydrate moieties play essential roles in fighting a
variety of bacterial and viral infections. Consequently, the design of new carbohydrate …

Amphiphilic dendrimers against antibiotic resistance: light at the end of the tunnel?

C Galanakou, D Dhumal, L Peng - Biomaterials Science, 2023 - pubs.rsc.org
With the alarming and prevailing antimicrobial resistance (AMR) comes an urgent need for
novel antimicrobial agents that are not only effective and robust but also do not induce …

Dynamic glycopeptide dendrimers: Synthesis and their controllable self-assembly into varied glyco-nanostructures for the biomimicry of glycans

F Bi, J Zhang, Z Wei, D Yu, S Zheng, J Wang… - …, 2021 - ACS Publications
A library of 14 dynamic glycopeptide amphiphilic dendrimers composed of 14 hydrophilic
and bioactive saccharides (seven kinds) as dendrons and 7 hydrophobic peptides (di-and …

Highly efficient functionalization of hydroxypropyl cellulose with glucuronic acid through click chemistry under microwave irradiation as potential biomaterial with …

A Flores, D Cañamares, LA Ticona, JL Pablos, J Peña… - Catalysis Today, 2024 - Elsevier
A straightforward and effective method to chemically conjugate hydroxypropyl cellulose
(HPC) to GlcA is described via microwave assisted copper-catalyzed azide-alkyne …

Towards Antibacterial Agents: Synthesis and Biological Activity of Multivalent Amide Derivatives of Thiacalix [4] Arene with Hydroxyl and Amine Groups

I Shiabiev, D Pysin, A Akhmedov, O Babaeva… - Pharmaceutics, 2023 - mdpi.com
Antimicrobial resistance to modern antibiotics stimulates the search for new ways to
synthesize and modify antimicrobial drugs. The development of synthetic approaches that …

Sequence-defined antibody-recruiting macromolecules

R Aksakal, C Tonneaux, A Uvyn, M Fossépré… - Chemical …, 2023 - pubs.rsc.org
Antibody-recruiting molecules represent a novel class of therapeutic agents that mediate the
recruitment of endogenous antibodies to target cells, leading to their elimination by the …

Exploring Rigid and Flexible Scaffolds to Develop Potent Glucuronic Acid Glycodendrimers for Dengue Virus Inhibition

A Merchán, P Ramírez-López, C Martínez… - Bioconjugate …, 2023 - ACS Publications
Multivalent glycodendrimers are valuable tools for studying carbohydrate–protein
interactions, and their scaffolds represent important components to increase specificity and …

Novel Approaches To Design Glycan‐Based Antibacterial Inhibitors

S Behren, U Westerlind - European Journal of Organic …, 2023 - Wiley Online Library
The interactions between bacterial lectins and carbohydrates on the host cell surface can
mediate bacterial adhesion, invasion, and immune evasion. Multivalency plays a key role in …

Development of sustainable synthesis of glucuronic acid glycodendrimers using ball milling and microwave-assisted CuAAC reaction

C García-Oliva, A Merchán, A Perona… - New Journal of …, 2022 - pubs.rsc.org
Two green strategies for copper-catalyzed azide–alkyne cycloaddition reaction based on
two activation pathways, solvent free mechanochemistry and microwave irradiation using a …