The literature on non-genetic peripheral biomarkers for major mental disorders is broad, with
conflicting results. An umbrella review of meta-analyses of non-genetic peripheral …

Reactive oxygen species (ROS) have been correlated with almost every human disease. Yet
clinical exploitation of these hypotheses by pharmacological modulation of ROS has been …

Subclinical inflammation has been associated with psychosis; however, it remains unknown
whether this phenomenon appears also in the premorbid phase. Therefore, we performed a …

Epidemiologic studies have shown that in the aging society, a person dies from stroke every
3 minutes and 42 seconds, and vast numbers of people experience depression around the …

Background The alterations of biological markers are thought to be effective tools to
understand the pathophysiology and management of major depressive disorder (MDD). A …

We aimed to perform a systematic review and meta-analysis of studies examining the levels
of chemokines in peripheral blood of patients with bipolar disorder (BD) and healthy …

About 10 million new cases of dementia develop worldwide each year, of which up to 70%
are attributable to Alzheimer's disease (AD). In addition to the widely known symptoms of …

It is established that purinergic signaling can shape a wide range of physiological functions,
including neurotransmission and neuromodulation. The purinergic system may play a role in …

Background Potential routes whereby systemic inflammation, oxidative stress and
mitochondrial dysfunction may drive the development of endothelial dysfunction and …

The association between schizophrenia (SZ) and uric acid (UA) levels has been suggested
for many years, but without solid evidence. Therefore, we conducted a systematic review …