Alzheimer's disease (AD) is pathologically defined by the presence of fibrillar amyloid β (Aβ)
peptide in extracellular senile plaques and tau filaments in intracellular neurofibrillary …

Oxidative stress, manifested by protein oxidation, lipid peroxidation, DNA oxidation and 3-
nitrotyrosine formation, among other indices, is observed in Alzheimer's disease (AD) brain …

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that currently affects
36 million people worldwide with no effective treatment available. Development of AD …

Transgenic mice overexpressing the P301L mutant human tau protein exhibit an
accumulation of hyperphosphorylated tau and develop neurofibrillary tangles. The …

Alzheimer's disease (AD) is a neurodegenerative disorder in which oxidative stress has
been implicated as an important event in the progression of the pathology. In particular, it …

Nitration of tyrosine in biological conditions represents a pathological event that is
associated with several neurodegenerative diseases, such as amyotrophic lateral sclerosis …

The presence of amyloid plaques in the brain is one of the pathological hallmarks of
Alzheimer's disease (AD). We report here a comprehensive proteomic analysis of senile …

Alzheimer's Disease (AD) is a neurodegenerative disease that affects cognition and is the
most common cause of dementia in the elderly. As the number of elderly individuals …

Alzheimer's disease (AD) is characterized by the presence of neurofibrillary tangles, senile
plaques and loss of synapses. There is accumulating evidence that oxidative stress plays an …

Oxidative stress is extensive in Alzheimer disease (AD) brain. Amyloid β‐peptide (1–42) has
been shown to induce oxidative stress and neurotoxicity in vitro and in vivo. Genetic …