Genetic and epigenetic factors influencing chronic kidney disease

LJ Smyth, S Duffy, AP Maxwell… - American Journal of …, 2014 - journals.physiology.org
Chronic kidney disease (CKD) has become a serious public health problem because of its
associated morbidity, premature mortality, and attendant healthcare costs. The rising …

Association of ACE1 I/D rs1799752 and ACE2 rs2285666 polymorphisms with the infection and severity of COVID‐19: A meta‐analysis

MA Aziz, MS Islam - Molecular Genetics & Genomic Medicine, 2022 - Wiley Online Library
Abstract Background ACE1 I/D rs1799752 and ACE2 rs2285666 genetic polymorphisms
could play a critical role in altering the clinical outcomes of SARS‐CoV‐2. The findings of …

The effect of ACE I/D polymorphisms alone and with concomitant risk factors on coronary artery disease

A Amara, M Mrad, A Sayeh, D Lahideb… - Clinical and Applied …, 2018 - journals.sagepub.com
Background: Coronary artery disease (CAD), also known as atherosclerotic heart disease, is
a leading cause of mortality and morbidity throughout the world. The role of …

[HTML][HTML] ACE Insertion/Deletion Polymorphism (rs4646994) Is Associated With the Increased Risk of Multiple Myeloma

S Zmorzynski, A Szudy-Szczyrek… - Frontiers in …, 2019 - frontiersin.org
Introduction: The insertion (I allele) deletion (D allele) polymorphism of ACE gene
(rs4646994) may influence the etiopathogenesis of multiple myeloma (MM). ACE gene is …

Association of ACE ID, MTHFR C677T, and MIF-173GC variants with the clinical course of COVID-19 patients

A Tekcan, M Cihangiroglu, M Capraz… - … Nucleotides & Nucleic …, 2023 - Taylor & Francis
The course of coronavirus disease-2019 (COVID-19) differs from person to person. The
relationship between the genetic variations of the host and the course of COVID-19 has …

Genetic and epigenetic risk factors for diabetic kidney disease

AJ McKnight, GJ McKay, AP Maxwell - Advances in chronic kidney disease, 2014 - Elsevier
Diabetes is increasing at daunting rates worldwide, and approximately 40% of affected
individuals will develop kidney complications. Diabetic kidney disease (DKD) is the leading …

[HTML][HTML] ALUminating the Path of Atherosclerosis Progression: Chaos Theory Suggests a Role for Alu Repeats in the Development of Atherosclerotic Vascular …

M Hueso, JM Cruzado, J Torras, E Navarro - International journal of …, 2018 - mdpi.com
Atherosclerosis (ATH) and coronary artery disease (CAD) are chronic inflammatory diseases
with an important genetic background; they derive from the cumulative effect of multiple …

Risk factors and therapies in vascular diseases: An umbrella review of updated systematic reviews and meta‐analyses

X Hong, J Lin, W Gu - Journal of cellular physiology, 2019 - Wiley Online Library
Aberrant blood vessel functioning and systemic circulation are key causes for vascular
disorders; cardiovascular, cerebrovascular, renal artery stenosis, and peripheral artery …

[HTML][HTML] Gene-gene and gene-environment interactions in meta-analysis of genetic association studies

C Lin, CM Chu, J Lin, HY Yang, SL Su - PloS one, 2015 - journals.plos.org
Extensive genetic studies have identified a large number of causal genetic variations in
many human phenotypes; however, these could not completely explain heritability in …

Genetic Variations Related to Angiotensin II Production and Risk for Basal Cell Carcinoma

I Gintoni, M Mastrogeorgiou, V Papakosta… - Biochemical …, 2024 - Springer
Basal cell carcinoma (BCC) is the most prevalent human neoplasm, with constantly
increasing annual incidence. Despite its slow growth, BCC is locally invasive and, if left …