The genomic plasticity of Candida albicans, a commensal and common opportunistic fungal
pathogen, continues to reveal unexpected surprises. Once thought to be asexual, we now …

Acquired azole resistance is a serious clinical problem that is often associated with the
appearance of aneuploidy and, in particular, with the formation of an isochromosome [i (5L)] …

The upsurge of immunocompromised patients has led to extensive study of fungal infections
with Candida albicans being the frontline model of pathogenic yeast in humans. In the quest …

Candida albicans is an opportunistic human fungal pathogen and is responsible for
candidiasis. Owing to the improvement in healthcare, the number of immunocompromised …

Minichromosomes possess functional centromeres and telomeres and thus should be stably
inherited. They offer an enormous opportunity to plant biotechnology as they have the …

Engineered minichromosomes offer an enormous opportunity to plant biotechnology as they
have the potential to simultaneously transfer and stably express multiple genes. Following a …

A reversible decrease or increase of Candida albicans chromosome copy number was
found to be a prevalent means of survival of this opportunistic pathogen, under conditions …

Electrophoretic karyotyping of the Candida albicans revealed a different migration pattern of
ChR in three different stocks of the sequencing strain SC5314. In one stock, the high …

We previously reported the occurrence of chromosome alterations in a Candida albicans
prototrophic strain 3153A treated with 5-fluoro-orotic acid (5-FOA). In this study we …

Candida albicans is a diploid fungus and a predominant opportunistic human pathogen.
Notably, C. albicans employs reversible chromosomal aneuploidies as a means of survival …