Curcumin is extracted from the rhizomes Curcuma longa L. It is known for its anti‐
inflammatory and anti‐oxidant activities. Despite its safety and potential for use against …

Cancer arises in the context of an in vivo tumor microenvironment. This microenvironment is
both a cause and consequence of tumorigenesis. Tumor and host cells co-evolve …

Background Despite several decades of research, managing body weight remains an
unsolved clinical problem. Health problems associated with dysregulated body weight, such …

Obesity is the result of the long‐term energy imbalance between the excess calories
consumed and the few calories expended. Reducing the intake of energy dense foods (fats …

Abstract Curcumin ((1E, 6E)− 1, 7‐bis (4‐hydroxy‐3‐methoxyphenyl)‐1, 6‐heptadiene‐3, 5‐
dione), the main component of the Indian spice turmeric, has been used in traditional …

Chronic inflammation, a pervasive feature of the aging process, is defined by a continuous,
multifarious, low-grade inflammatory response. It is a sustained and systemic phenomenon …

Abstract Background 7, 8-Dihydroxyflavone (7, 8-DHF) is a small molecular weight
compound that mimics the functions of brain-derived neurotrophic factor (BDNF). The current …

Background Dietary bioactive compounds capable of improving metabolic profiles would be
of great value, especially for overweight individuals undergoing a caloric restriction (CR) …

Time-restricted feeding (TRF) limits the duration of food availability without altering diet
composition and can combat obesity in humans and mice. For this study we evaluated the …

Background: Accumulating experimental data supports the capacity of natural compounds to
intervene in complicated molecular pathways underlying the pathogenesis of certain human …