Arynes are among the most active organic intermediates and have found numerous
applications in expeditious preparation of substituted arenes. In the past 20 years, chemists …

Additions of homoelement-element and heteroelementelement linkages to unsaturated
substrates catalyzed by the platinum group metals constitute synthetically highly versatile …

Organosilicon compounds act as a nucleophile upon activation by an appropriate base and
behave in a manner similar to main-group organometallic reagents. In the last decades …

Arynes are neutral intermediates in which two adjacent atoms of an aromatic ring lack
substituents, thus leaving two atomic orbitals (perpendicular to the aromatic x system) to …

An efficient, transition-metal-free procedure for the N-arylation of amines, sulfonamides, and
carbamates and O-arylation of phenols and carboxylic acids has been achieved by allowing …

Benzyne Click Chemistry: Synthesis of Benzotriazoles from Benzynes and Azides | Organic
Letters ACS ACS Publications C&EN CAS Find my institution Log In Organic Letters ACS …

An efficient, mild, transition-metal-free method has been developed for the intermolecular C−
N σ-bond addition of amides and S− N σ-bond addition of sulfinamides to arynes to form one …

Transition metal‐catalyzed bissilylation reactions of alkynes with disilane reagents have
become one of the most straightforward and efficient protocols to rapidly produce structurally …

It is well known that the high strain created by the formal triple bond of arynes makes these
compounds powerful electrophiles.[1] The addition of a nucleophile X to benzyne leads to …

Aryne compounds are highly reactive intermediates that have been widely used in organic
synthesis.[1, 2] In recent years, studies on aryne-based reactions have achieved some …