Cadherin family includes lists of transmembrane glycoproteins which mediate calcium-
dependent cell-cell adhesion. Cadherin-mediated adhesion regulates cell growth and …

DNA methylation is one of the most intensely studied epigenetic modifications in mammals.
In normal cells, it assures the proper regulation of gene expression and stable gene …

We review the role of cadherins and cadherin-related proteins in human cancer. Cellular
and animal models for human cancer are also dealt with whenever appropriate. E-cadherin …

The cadherin molecules at adherens junctions have multiple isoforms. Cadherin isoform
switching (cadherin switching) occurs during normal developmental processes to allow cell …

Epithelial–mesenchymal transition (EMT) is a process whereby epithelial cells are
transcriptionally reprogrammed, resulting in decreased adhesion and enhanced migration …

Changes in human DNA methylation patterns are an important feature of cancer
development and progression and a potential role in other conditions such as …

In the last years, mortality from breast cancer has declined in western countries as a
consequence of a more widespread screening resulting in earlier detection, as well as an …

E-cadherin and P-cadherin are major contributors to cell–cell adhesion in epithelial tissues,
playing pivotal roles in important morphogenetic and differentiation processes during …

Epigenetic changes can be defined as stable molecular alterations of a cellular phenotype
such as the gene expression profile of a cell that are heritable during somatic cell divisions …

The enormous biologic complexity of human cancer has stimulated the development of more
appropriate experimental models that could resemble in a natural and spontaneous manner …