The cycloaddition of azides to alkynes is one of the most important synthetic routes to 1 H-[1,
2, 3]-triazoles. Here a novel regiospecific copper (I)-catalyzed 1, 3-dipolar cycloaddition of …

From CO(2) to Methanol by Hybrid QM/MM Embedding This work was supported by EU
Esprit IV project 25047. SAF is grateful to ICI and Synetix for funding. K. Waugh, L. Whitmore …

Massachusetts Institute of Technology Cambridge, MA 02139 (USA) Fax:(1) 617-253-7929
E-mail: seeberg@ mit. edu [**] Financial support from the donors of the Petroleum Research …

N‐formylation is a common pre‐and post‐translational modification of the N‐terminus or the
lysine side chain of peptides and proteins that plays a role in the initiation of immune …

Several new α‐azido acids have been synthesized and their use in solid‐phase peptide
synthesis has been demonstrated. The azido group allows for high activation of the carboxyl …

General conditions for efficient on-resin N-formylation of peptides were identified by
screening of a number of reagents comprising aliphatic formates (ethyl formate, 2, 2, 2 …

A series of analogues of efrapeptin C (1), with variations in the central tripeptide epitope
(positions 6–8), were prepared by a combination of solid‐and solution‐phase peptide …

A small library of peptide analogues of the chemotactic tripeptide For‐Met‐Leu‐Phe‐NH2
modified by substitution of Leu at position 2 by three different fluorinated amino acids …

We report here the synthesis and activity of new analogs of the N-formyl and N-tert-
butyloxycarbonyl (Boc) derivatives of the tripeptide Met-Leu-Phe-OMe containing an achiral …

An industrially attractive L-specific amidase was purified to homogeneity from Ochrobactrum
anthropi NCIMB 40321 wild-type cells. The purified amidase displayed maximum initial …