Antiviral activity exerted by natural products against human viruses
M Musarra-Pizzo, R Pennisi, I Ben-Amor, G Mandalari… - Viruses, 2021 - mdpi.com
Viral infections are responsible for several chronic and acute diseases in both humans and
animals. Despite the incredible progress in human medicine, several viral diseases, such as …
animals. Despite the incredible progress in human medicine, several viral diseases, such as …
Machine learning techniques applied to the drug design and discovery of new antivirals: a brief look over the past decade
MSM Serafim, VS dos Santos Júnior… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction: Drug design and discovery of new antivirals will always be extremely important
in medicinal chemistry, taking into account known and new viral diseases that are yet to …
in medicinal chemistry, taking into account known and new viral diseases that are yet to …
Cheminformatics-based identification of potential novel anti-SARS-CoV-2 natural compounds of African origin
The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute
respiratory syndrome virus 2 (SARS-CoV-2) has impacted negatively on public health and …
respiratory syndrome virus 2 (SARS-CoV-2) has impacted negatively on public health and …
[HTML][HTML] A SARS-CoV-2 vaccine candidate: In-silico cloning and validation
SARS-CoV-2 is spreading globally at a rapid pace. To contain its spread and prevent further
fatalities, the development of a vaccine against SARS-CoV-2 is an urgent prerequisite. Thus …
fatalities, the development of a vaccine against SARS-CoV-2 is an urgent prerequisite. Thus …
Revolutionizing anti-cancer drug discovery against breast cancer and lung cancer by modification of natural genistein: an advanced computational and drug design …
Breast and lung cancer are two of the most lethal forms of cancer, responsible for a
disproportionately high number of deaths worldwide. Both doctors and cancer patients …
disproportionately high number of deaths worldwide. Both doctors and cancer patients …
Network pharmacology of iridoid glycosides from Eucommia ulmoides Oliver against osteoporosis
T Wang, L Fan, S Feng, X Ding, X An, J Chen… - Scientific reports, 2022 - nature.com
Eucommia ulmoides Oliver is one of the commonly used traditional Chinese medicines for
the treatment of osteoporosis, and iridoid glycosides are considered to be its active …
the treatment of osteoporosis, and iridoid glycosides are considered to be its active …
Computational identification of potential anti-inflammatory natural compounds targeting the p38 mitogen-activated protein kinase (MAPK): Implications for COVID-19 …
Severely ill coronavirus disease 2019 (COVID-19) patients show elevated concentrations of
pro-inflammatory cytokines, a situation commonly known as a cytokine storm. The p38 …
pro-inflammatory cytokines, a situation commonly known as a cytokine storm. The p38 …
Cheminformatics-based study identifies potential ebola VP40 inhibitors
The Ebola virus (EBOV) is still highly infectious and causes severe hemorrhagic fevers in
primates. However, there are no regulatorily approved drugs against the Ebola virus disease …
primates. However, there are no regulatorily approved drugs against the Ebola virus disease …
[HTML][HTML] Multi-target potential of Indian phytochemicals against SARS-CoV-2: A docking, molecular dynamics and MM-GBSA approach extended to Omicron B. 1.1 …
J Roshni, R Vaishali, KS Ganesh, N Dharani… - Journal of infection and …, 2022 - Elsevier
Abstract Background SARS-CoV-2, an emerged strain of corona virus family became almost
serious health concern worldwide. Despite vaccines availability, reports suggest the …
serious health concern worldwide. Despite vaccines availability, reports suggest the …
Artificial Intelligence, machine learning, and big data for Ebola virus drug discovery
The effect of Ebola virus disease (EVD) is fatal and devastating, necessitating several efforts
to identify potent biotherapeutic molecules. This review seeks to provide perspectives on …
to identify potent biotherapeutic molecules. This review seeks to provide perspectives on …