How does HIV cause AIDS?
RA Weiss - Science, 1993 - science.org
Many questions have been posed about acquired immunodeficiency syndrome (AIDS)
pathogenesis. Is human immunodeficiency virus (HIV) both necessary and sufficient to …
pathogenesis. Is human immunodeficiency virus (HIV) both necessary and sufficient to …
The immunopathogenesis of human immunodeficiency virus infection
G Pantaleo, C Graziosi, AS Fauci - New England Journal of …, 1993 - Mass Medical Soc
The human immunodeficiency virus (HIV) is probably the most intensively studied virus in
the history of biomedical research. A large number of distinct isolates have been cloned and …
the history of biomedical research. A large number of distinct isolates have been cloned and …
Pathogenesis of human immunodeficiency virus infection
JA Levy - Microbiological reviews, 1993 - Am Soc Microbiol
The lentivirus human immunodeficiency virus (HIV) causes AIDS by interacting with a large
number of different cells in the body and escaping the host immune response against it. HIV …
number of different cells in the body and escaping the host immune response against it. HIV …
[图书][B] HIV and the pathogenesis of AIDS.
JA Levy - 1994 - cabidigitallibrary.org
This book grew out of a scientific review, originally published in Microbiological Reviews. It
has been updated and expanded-now citing more than 2100 references (100 pages of the …
has been updated and expanded-now citing more than 2100 references (100 pages of the …
Multifactorial nature of human immunodeficiency virus disease: implications for therapy
AS Fauci - Science, 1993 - science.org
The immunopathogenic mechanisms underlying human immunodeficiency virus (HIV)
disease are extremely complex; the disease process is multifactorial with multiple …
disease are extremely complex; the disease process is multifactorial with multiple …
HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune …
M Connors, JA Kovacs, S Krevat… - Nature medicine, 1997 - nature.com
Abstract Changes in CD4+ T-cell surface marker phenotype and antigen receptor (TCR)
repertoire were examined during the course of HIV infection and following therapy. A …
repertoire were examined during the course of HIV infection and following therapy. A …
Cellular receptors and viral glycoproteins involved in retrovirus entry
RA Weiss - The retroviridae, 1993 - Springer
The initial steps in virus infection involve the binding of virions to specific cell surface
receptors. Following the attachment of enveloped viruses, further events lead to membrane …
receptors. Following the attachment of enveloped viruses, further events lead to membrane …
Present status and future prospects for HIV therapies
MI Johnston, DF Hoth - Science, 1993 - science.org
Since the discovery of human immunodeficiency virus (HIV) in 1983, significant progress
has been made toward the discovery, development, and licensing of anti-HIV drugs. In vitro …
has been made toward the discovery, development, and licensing of anti-HIV drugs. In vitro …
Early protective effect ofCCR-5A32 heterozygosity on HIV-1 disease progression: relationship with viral load
L Meyer, M Magierowska, JB Hubert, C Rouzioux… - Aids, 1997 - journals.lww.com
Objective: To determine the influence of heterozygosity for the A32 mutant CCR-5 allele on
HIV-1 disease progression. Design: HIV-1 disease progression and serum viral load were …
HIV-1 disease progression. Design: HIV-1 disease progression and serum viral load were …
Hepatitis C virus variants circumventing cytotoxic T lymphocyte activity as a mechanism of chronicity
SL Tsai, YM Chen, MH Chen, CY Huang, IS Sheen… - Gastroenterology, 1998 - Elsevier
Background & Aims: High rate of chronicity after acute hepatitis C virus (HCV) infection
cannot be explained in the presence of a multispecific cytotoxic T lymphocyte (CTL) …
cannot be explained in the presence of a multispecific cytotoxic T lymphocyte (CTL) …