Male reproductive disorders and fertility trends: influences of environment and genetic susceptibility

NE Skakkebaek, E Rajpert-De Meyts… - Physiological …, 2016 - journals.physiology.org
It is predicted that Japan and European Union will soon experience appreciable decreases
in their populations due to persistently low total fertility rates (TFR) below replacement level …

[HTML][HTML] Effects of maternal obesity on placental function and fetal development

KR Howell, TL Powell - Reproduction (Cambridge, England), 2017 - ncbi.nlm.nih.gov
Obesity has reached epidemic proportions and pregnancies in obese mothers have
increased risk for complications including gestational diabetes, hypertensive disorders …

Possible fetal determinants of male infertility

A Juul, K Almstrup, AM Andersson, TK Jensen… - Nature Reviews …, 2014 - nature.com
Although common reproductive problems, such as male infertility and testicular cancer,
present in adult life, strong evidence exists that these reproductive disorders might have a …

Frequency, morbidity and equity—the case for increased research on male fertility

S Kimmins, RA Anderson, CLR Barratt… - Nature Reviews …, 2024 - nature.com
Currently, most men with infertility cannot be given an aetiology, which reflects a lack of
knowledge around gamete production and how it is affected by genetics and the …

The impact of obesity on male fertility

TJG Chambers, RA Anderson - Hormones, 2015 - Springer
Obesity in men of reproductive age is globally on the increase. There is clear evidence from
epidemiological studies that obesity impacts negatively on male fertility; it is associated with …

Nitrate: an environmental endocrine disruptor? A review of evidence and research needs

R Poulsen, N Cedergreen, T Hayes… - … science & technology, 2018 - ACS Publications
Nitrate is heavily used as an agricultural fertilizer and is today a ubiquitous environmental
pollutant. Environmental endocrine effects caused by nitrate have received increasing …

[HTML][HTML] Populations, decreasing fertility, and reproductive health

NE Skakkebaek, N Jørgensen, AM Andersson, A Juul… - The Lancet, 2019 - thelancet.com
conveys an extremely important message about international population trends that have so
far received little public attention. For more than 40 years, birth rates in industrialised …

Two simple cleanup methods combined with LC-MS/MS for quantification of steroid hormones in in vivo and in vitro assays

JJ Weisser, CH Hansen, R Poulsen, LW Larsen… - Analytical and …, 2016 - Springer
Measuring both progestagens, androgens, corticosteroids as well as estrogens with a single
method makes it possible to investigate the effects of endocrine-disrupting chemicals …

[HTML][HTML] Persistent environmental pollutants and couple fecundity: an overview

GMB Louis - Reproduction, 2014 - rep.bioscientifica.com
Speculation has arisen that human fecundity may be declining, possibly a function of
exposure to persistent environmental chemicals that resist degradation resulting in various …

[HTML][HTML] NRF2 loss recapitulates heritable impacts of paternal cigarette smoke exposure

PJ Murphy, J Guo, TG Jenkins, ER James… - PLoS …, 2020 - journals.plos.org
Paternal cigarette smoke (CS) exposure is associated with increased risk of behavioral
disorders and cancer in offspring, but the mechanism has not been identified. Here we use …