Animal models of traumatic brain injury

Y Xiong, A Mahmood, M Chopp - Nature Reviews Neuroscience, 2013 - nature.com
Traumatic brain injury (TBI) is a leading cause of mortality and morbidity both in civilian life
and on the battlefield worldwide. Survivors of TBI frequently experience long-term disabling …

A review of post-concussion syndrome and psychological factors associated with concussion

DK Broshek, AP De Marco, JR Freeman - Brain injury, 2015 - Taylor & Francis
Objective: This study reviewed several topics related to post-concussion syndrome and
psychological factors associated with concussion. Topics include neurobiological …

Factors influencing behavior in the forced swim test

OV Bogdanova, S Kanekar, KE D'Anci… - Physiology & …, 2013 - Elsevier
The forced swim test (FST) is a behavioral test in rodents which was developed in 1978 by
Porsolt and colleagues as a model for predicting the clinical efficacy of antidepressant …

Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects

FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

Animal modelling of traumatic brain injury in preclinical drug development: where do we go from here?

N Marklund, L Hillered - British journal of pharmacology, 2011 - Wiley Online Library
Traumatic brain injury (TBI) is the leading cause of death and disability in young adults.
Survivors of TBI frequently suffer from long‐term personality changes and deficits in …

The effect of injury severity on behavior: a phenotypic study of cognitive and emotional deficits after mild, moderate, and severe controlled cortical impact injury in mice

PM Washington, PA Forcelli, T Wilkins… - Journal of …, 2012 - liebertpub.com
Traumatic brain injury (TBI) can cause a broad array of behavioral problems including
cognitive and emotional deficits. Human studies comparing neurobehavioral outcomes after …

Mesenchymal stem cell therapy for the treatment of traumatic brain injury: progress and prospects

M Das, K Mayilsamy, SS Mohapatra… - Reviews in the …, 2019 - degruyter.com
Traumatic brain injury (TBI) is a major cause of injury-related mortality and morbidity in the
USA and around the world. The survivors may suffer from cognitive and memory deficits …

Sodium selenate reduces hyperphosphorylated tau and improves outcomes after traumatic brain injury

SR Shultz, DK Wright, P Zheng, R Stuchbery, SJ Liu… - Brain, 2015 - academic.oup.com
Traumatic brain injury is a common and serious neurodegenerative condition that lacks a
pharmaceutical intervention to improve long-term outcome. Hyperphosphorylated tau is …

Quercetin prevents chronic unpredictable stress induced behavioral dysfunction in mice by alleviating hippocampal oxidative and inflammatory stress

V Mehta, A Parashar, M Udayabanu - Physiology & Behavior, 2017 - Elsevier
It is now evident that chronic stress is associated with anxiety, depression and cognitive
dysfunction and very few studies have focused on identifying possible methods to prevent …

Issues related to symptomatic and disease‐modifying treatments affecting cognitive and neuropsychiatric comorbidities of epilepsy

AR Brooks‐Kayal, KG Bath, AT Berg… - …, 2013 - Wiley Online Library
Many symptoms of neurologic or psychiatric illness—such as cognitive impairment,
depression, anxiety, attention deficits, and migraine—occur more frequently in people with …