MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …

It has been almost two decades since the first link between microRNAs and cancer was
established. In the ensuing years, this abundant class of short noncoding regulatory RNAs …

The immunological synapse is a molecular hub that facilitates the delivery of three activation
signals, namely antigen, costimulation/corepression and cytokines, from antigen-presenting …

A significant fraction of mature miRNA transcripts carries sequence and/or length variations,
termed isomiRs. IsomiRs are differentially abundant in cell types, tissues, body fluids or …

Alzheimer's disease (AD), the leading form of dementia, is associated with abnormal tau and
β-amyloid accumulation in the brain. We conducted a miRNA-seq study to identify miRNAs …

IsomiRs, sequence variants of mature microRNAs, are usually detected and quantified using
high-throughput sequencing. Many examples of their biological relevance have been …

Breast cancer (BC) is the most diagnosed cancer in women and the second most common
cancer globally. Significant advances in BC research have led to improved early detection …

Abstract The NCBI Sequence Read Archive currently hosts microRNA sequencing data for
over 800 different species, evidencing the existence of a broad taxonomic distribution in the …

Simple Summary Malignant melanoma spreads to other organs and is resistant in part due
to the presence of cancer stem cell subpopulations (CSCs). To combat these aggressive …

Wheat is one of the most important food sources on Earth. MicroRNAs (miRNAs) play
important roles in wheat productivity. To identify wheat miRNAs as well as their expression …