Transdermal fentanyl: a review of its pharmacological properties and therapeutic efficacy in pain control
W Jeal, P Benfield - Drugs, 1997 - Springer
Fentanyl is a synthetic opioid with short-acting analgesic activity after intravenous or
subcutaneous administration. The low molecular weight, high potency and lipid solubility of …
subcutaneous administration. The low molecular weight, high potency and lipid solubility of …
Opioid rotation for cancer pain: rationale and clinical aspects
S Mercadante - … International Journal of the American Cancer …, 1999 - Wiley Online Library
BACKGROUND Some patients with cancer pain may develop uncontrolled adverse effects,
including generalized myoclonus, delirium, nausea and emesis, or severe sedation before …
including generalized myoclonus, delirium, nausea and emesis, or severe sedation before …
[HTML][HTML] Transdermal fentanyl versussustained-release oral morphine in cancer pain: Preference, efficacy, and quality of life
S Ahmedzai, D Brooks… - Journal of pain and …, 1997 - Elsevier
Cancer patients requiring strong opioid analgesia (n= 202; mean age, 61.5 years; range, 18–
89 years; 55% men) were recruited from 38 United Kingdom palliative care centers into a …
89 years; 55% men) were recruited from 38 United Kingdom palliative care centers into a …
Clinical pharmacokinetics of transdermal opioids: focus on transdermal fentanyl
S Grond, L Radbruch, KA Lehmann - Clinical pharmacokinetics, 2000 - Springer
Transdermal delivery allows continuous systemic application of opioids through the intact
skin. This review analyses the pharmacokinetic properties of transdermal opioid …
skin. This review analyses the pharmacokinetic properties of transdermal opioid …
Benefit-risk assessment of transdermal fentanyl for the treatment of chronic pain
CA Kornick, J Santiago-Palma, N Moryl, R Payne… - Drug Safety, 2003 - Springer
Transdermal fentanyl is effective and well tolerated for the treatment of chronic pain caused
by malignancy and non-malignant conditions when administered according to the …
by malignancy and non-malignant conditions when administered according to the …
Strategies for the treatment of cancer pain in the new millennium
C Ripamonti, ED Dickerson - Drugs, 2001 - Springer
As was the case in the era before us, in the new millennium we will continue to see an
abundance of patients experiencing cancer-related pain for different reasons. Although …
abundance of patients experiencing cancer-related pain for different reasons. Although …
[HTML][HTML] A clinical evaluation of transdermal therapeutic system fentanyl for the treatment of cancer pain
PA Sloan, DE Moulin, H Hays - Journal of pain and symptom management, 1998 - Elsevier
Fentanyl has been incorporated into a transdermal therapeutic system (TTS) containing a
rate-limiting membrane that provides constant release of the opioid. TTS fentanyl provides …
rate-limiting membrane that provides constant release of the opioid. TTS fentanyl provides …
Transdermal fentanyl for the management of cancer pain: a survey of 1005 patients
L Radbruch, R Sabatowski, F Petzke… - Palliative …, 2001 - journals.sagepub.com
Transdermal fentanyl was released in Germany in 1995. From October 1996 to February
1998 transdermal treatment was documented for 1005 patients (506 men and 499 women …
1998 transdermal treatment was documented for 1005 patients (506 men and 499 women …
[HTML][HTML] A comparison of subcutaneous morphine and fentanyl in hospice cancer patients
R Hunt, B Fazekas, D Thorne, M Brooksbank - Journal of pain and …, 1999 - Elsevier
This study compares subcutaneous (sc) morphine and fentanyl with respect to pain control
and side effects using a 6-day randomized, double-blind, cross-over design. Results were …
and side effects using a 6-day randomized, double-blind, cross-over design. Results were …
[HTML][HTML] Reduction in constipation and laxative requirements following opioid rotation to methadone: a report of four cases
PJ Daeninck, E Bruera - Journal of pain and symptom management, 1999 - Elsevier
Constipation is a common symptom in cancer patients, especially in those who are receiving
opioid analgesics for pain. Although several articles have recently examined constipation …
opioid analgesics for pain. Although several articles have recently examined constipation …