Objectives To estimate procedure‐related risks of miscarriage following amniocentesis and
chorionic villus sampling (CVS) based on a systematic review of the literature and a meta …

Haemophilia A and B are hereditary haemorrhagic disorders characterised by deficiency or
dysfunction of coagulation protein factors VIII and IX, respectively. Recurrent joint and …

Noninvasive prenatal genetic testing (NIPT) is an advance in the detection of fetal
chromosomal aneuploidies that analyzes cell-free fetal DNA in the blood of a pregnant …

Preimplantation Genetic Diagnosis and Screening (PGD/PGS) for monogenic diseases
and/or numerical/structural chromosomal abnormalities is a tool for embryo testing aimed at …

Introduction: As a consequence of the introduction of effective screening methods, the
number of invasive prenatal diagnostic procedures is steadily declining. The aim of this …

Context Noninvasive prenatal determination of fetal sex using cell-free fetal DNA provides
an alternative to invasive techniques for some heritable disorders. In some countries this …

Objective To assess prospectively the risk of fetal loss associated with chorionic villus
sampling (CVS) and amniocentesis (AC) following combined first‐trimester screening (cFTS) …

ISUOG Practice Guidelines: invasive procedures for prenatal diagnosis ISUOG Practice
Guidelines: invasive procedures for prenatal diagnosis Ultrasound Obstet Gynecol. 2016 …

Noninvasive prenatal testing (NIPT) has had a profound influence in the field of prenatal
diagnosis since the 1997 discovery of cell‐free fetal DNA in maternal blood. Research has …

Objective As the first laboratory to offer massively parallel sequencing-based noninvasive
prenatal testing (NIPT) for fetal aneuploidies, Sequenom Laboratories has been able to …