• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Cardiovascular diseases (CVDs) are the main cause of death among patients with type 2
diabetes mellitus (T2DM), particularly in low-and middle-income countries. To effectively …

Abstract Aim The “2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management
of Patients With Chronic Coronary Disease” provides an update to and consolidates new …

Importance Acute coronary syndromes (ACS) are characterized by a sudden reduction in
blood supply to the heart and include ST-segment elevation myocardial infarction (STEMI) …

For many years, bleeding has been perceived as an unavoidable consequence of strategies
aimed at reducing thrombotic complications in patients undergoing percutaneous coronary …

Cardiovascular disease and cancer are the 2 leading causes of death worldwide. Emerging
evidence suggests common mechanisms between cancer and cardiovascular disease …

Importance Patients who are candidates for percutaneous coronary intervention (PCI) and
are at high bleeding risk constitute a therapeutic challenge because they often also face an …

Most agonists stimulate platelet Ca2+ rises via G-protein coupled receptors (GPCRs) or
ITAM-linked receptors (ILRs). Well studied are the GPCRs stimulated by the soluble agonists …

Background It is still unknown which antiplatelet monotherapy should be continued after a
period of dual antiplatelet therapy (DAPT) in patients undergoing percutaneous coronary …

The incidence of frailty and cardiovascular disease (CVD) increases as the population ages.
There is a bidirectional relationship between frailty and CVD, and both conditions share …