Chloramphenicol (CAM) is the D-threo isomer of a small molecule, consisting of ap-
nitrobenzene ring connected to a dichloroacetyl tail through a 2-amino-1, 3-propanediol …

The increase in multi-drug-resistant bacteria is limiting the effectiveness of currently
approved antibiotics, leading to a renewed interest in antibiotics with distinct chemical …

Antibiotic chloramphenicol (CHL) binds with a moderate affinity at the peptidyl transferase
center of the bacterial ribosome and inhibits peptide bond formation. As an approach for …

Chloramphenicol (CAM), the bacteriostatic broad-spectrum antibiotic, isolated from
Streptomyces venezuelae during the “golden era” of antibiotic discovery, nowadays has …

In the current work, in continuation of our recent research, we synthesized and studied new
chimeric compounds, including the ribosome-targeting antibiotic chloramphenicol (CHL) …

The WaterLOGSY (WL) and saturation transfer difference (STD) NMR experiments have
proven to be extremely useful techniques to characterize interactions between small …

Chloramphenicol (CHL) is a ribosome-targeting antibiotic that binds to the peptidyl
transferase center (PTC) of the bacterial ribosome and inhibits peptide bond formation. As …

Saxaul (Haloxylon ammodendron) is the most widespread plant community in the Gobi
Desert in Mongolia, which plays important roles in wind control, sand fixation and water …

In a previous study published by our group, successful modification of the antibiotic
chloramphenicol (CHL) was reported, which was achieved by replacing the dichloroacetyl …

A novel amide alkaloid, bursatamide A (1), featuring an unprecedented propyl-
hexahydronaphthalene carbon framework, was isolated from the infrequently studied sea …