Astrocytes play essential roles in development, homeostasis, injury, and repair of the central
nervous system (CNS). Their development is tightly regulated by distinct spatial and …

The inability of damaged neurons to regenerate within the mature central nervous system
(CNS) is a significant neuroscientific challenge. Astrocytes are an essential component of …

Astrocytes fulfil many functions in the central nervous system (CNS), including contribution to
the blood brain barrier, synapse formation, and trophic support. In addition, they can mount …

Non‑coding RNAs, particularly long non‑coding RNAs (lncRNAs), play important roles in
tumorigenesis. The miR‑155 host gene (MIR155HG) lncRNA has been found to play a …

We present a highly fluorescent, solvatochromic, 1, 8-naphthalimide for simultaneous
imaging of lipid droplets and endoplasmic reticulum, with distinguishable emission maxima …

Background The conversion of astrocytes activated by nerve injuries to oligodendrocytes is
not only beneficial to axonal remyelination, but also helpful for reversal of glial scar. Recent …

Background Metformin has been introduced as a neuroprotective agent in recent years.
Here we evaluate the therapeutic effects of metformin in sporadic mouse model of …

Background Spinal cord injury (SCI) results in glial scar formation and irreversible neuronal
loss, which finally leads to functional impairments and long-term disability. Our previous …

Astrocytes are the most abundant cell type in the central nervous system, carrying out a wide
spectrum of biological functions. During early development, neural progenitor cells in the …

Background Pregnenolone is a precursor of various steroid hormones involved in osteoblast
proliferation, microtubules polymerization and cell survival protection. Previous reports …