[HTML][HTML] Toll-like receptor-guided therapeutic intervention of human cancers: molecular and immunological perspectives
Toll-like receptors (TLRs) serve as the body's first line of defense, recognizing both
pathogen-expressed molecules and host-derived molecules released from damaged or …
pathogen-expressed molecules and host-derived molecules released from damaged or …
Programmed cell death pathways as targets for developing antifilarial drugs: Lessons from the recent findings
NC Das, P Chakraborty, S Nandy, A Dey… - Journal of Cellular …, 2023 - Wiley Online Library
More than half a century has passed since the introduction of the National Filariasis Control
Program; however, as of 2023, lymphatic filariasis (LF) still prevails globally, particularly in …
Program; however, as of 2023, lymphatic filariasis (LF) still prevails globally, particularly in …
[HTML][HTML] Designing efficient multi-epitope peptide-based vaccine by targeting the antioxidant thioredoxin of bancroftian filarial parasite
Thioredoxin is a low molecular weight redox-active protein of filarial parasite that plays a
crucial role in downregulating the host immune response to prolong the survival of the …
crucial role in downregulating the host immune response to prolong the survival of the …
Reverse vaccinology assisted design of a novel multi-epitope vaccine to target Wuchereria bancrofti cystatin: An immunoinformatics approach
Proteases are the critical mediators of immunomodulation exerted by the filarial parasites to
bypass and divert host immunity. Cystatin is a small (∼ 15 kDa) immunomodulatory filarial …
bypass and divert host immunity. Cystatin is a small (∼ 15 kDa) immunomodulatory filarial …
Peptide-Based Therapeutic HPV Cancer Vaccine Synthesized via Bacterial Outer Membrane Vesicles
H Chen, X Zheng, L Li, L Huang… - International Journal of …, 2023 - Taylor & Francis
Background Peptide-based vaccines have broad application prospects because of their
safety, simple preparation, and effectiveness, especially in the development of personalized …
safety, simple preparation, and effectiveness, especially in the development of personalized …
Synthesis of smart graphene quantum dots: A benign biomaterial for prominent intracellular imaging and improvement of drug efficacy
The present study portrays the synthesis, characterization and different biological
applications of hetero atoms (N and S) doped smart graphene quantum dots (NS-GQD). NS …
applications of hetero atoms (N and S) doped smart graphene quantum dots (NS-GQD). NS …
In-silico evidences on filarial cystatin as a putative ligand of human TLR4
Cystatin is a small molecular weight immunomodulatory protein of filarial parasite that plays
a pivotal role in downregulating the host immune response to prolong the survival of the …
a pivotal role in downregulating the host immune response to prolong the survival of the …
Designing of a novel multi-epitope peptide based vaccine against Brugia malayi: An in silico approach
In spite of the tremendous efforts of the World Health Organization, scientific and medical
community to eradicate lymphatic filariasis (LF) within 2020, the disease is still taking a huge …
community to eradicate lymphatic filariasis (LF) within 2020, the disease is still taking a huge …
Scolicidal and apoptotic effects of phyto-and chemically synthesized silver/boehmite nanocomposites on Echinococcus granulosus protoscoleces
Cystic hydatid disease (CHD) is a zoonotic disease caused by the larval stage of
Echinococcus granulosus (E. granulosus). This study aimed to synthesize silver …
Echinococcus granulosus (E. granulosus). This study aimed to synthesize silver …
Model nematodes as a practical innovation to promote high throughput screening of natural products for anthelmintics discovery in South Asia: Current challenges …
With the increasing prevalence of anthelmintic resistance in animals recorded globally, and
the threat of resistance in human helminths, the need for novel anthelmintic drugs is greater …
the threat of resistance in human helminths, the need for novel anthelmintic drugs is greater …