Artificial intelligence-based multi-omics analysis fuels cancer precision medicine

X He, X Liu, F Zuo, H Shi, J Jing - Seminars in Cancer Biology, 2023 - Elsevier
With biotechnological advancements, innovative omics technologies are constantly
emerging that have enabled researchers to access multi-layer information from the genome …

Artificial intelligence in digital pathology—new tools for diagnosis and precision oncology

K Bera, KA Schalper, DL Rimm, V Velcheti… - Nature reviews Clinical …, 2019 - nature.com
In the past decade, advances in precision oncology have resulted in an increased demand
for predictive assays that enable the selection and stratification of patients for treatment. The …

Artificial intelligence for clinical oncology

BH Kann, A Hosny, HJWL Aerts - Cancer Cell, 2021 - cell.com
Clinical oncology is experiencing rapid growth in data that are collected to enhance cancer
care. With recent advances in the field of artificial intelligence (AI), there is now a …

Prostate cancer, version 2.2019, NCCN clinical practice guidelines in oncology

JL Mohler, ES Antonarakis, AJ Armstrong… - Journal of the National …, 2019 - jnccn.org
The NCCN Guidelines for Prostate Cancer include recommendations regarding diagnosis,
risk stratification and workup, treatment options for localized disease, and management of …

Genetics and biology of prostate cancer

G Wang, D Zhao, DJ Spring… - Genes & …, 2018 - genesdev.cshlp.org
Despite the high long-term survival in localized prostate cancer, metastatic prostate cancer
remains largely incurable even after intensive multimodal therapy. The lethality of advanced …

The 2019 Genitourinary Pathology Society (GUPS) white paper on contemporary grading of prostate cancer

JI Epstein, MB Amin, SW Fine… - … of pathology & …, 2021 - meridian.allenpress.com
Context.—Controversies and uncertainty persist in prostate cancer grading. Objective.—To
update grading recommendations. Data Sources.—Critical review of the literature along with …

Predicting tumour radiosensitivity to deliver precision radiotherapy

JM Price, A Prabhakaran, CML West - Nature Reviews Clinical …, 2023 - nature.com
Owing to advances in radiotherapy, the physical properties of radiation can be optimized to
enable individualized treatment; however, optimization is rarely based on biological …

Impact of molecular subtypes in muscle-invasive bladder cancer on predicting response and survival after neoadjuvant chemotherapy

R Seiler, HAD Ashab, N Erho, BWG van Rhijn… - European urology, 2017 - Elsevier
Background An early report on the molecular subtyping of muscle-invasive bladder cancer
(MIBC) by gene expression suggested that response to neoadjuvant chemotherapy (NAC) …

[HTML][HTML] Translating RNA sequencing into clinical diagnostics: opportunities and challenges

SA Byron, KR Van Keuren-Jensen… - Nature Reviews …, 2016 - nature.com
With the emergence of RNA sequencing (RNA-seq) technologies, RNA-based biomolecules
hold expanded promise for their diagnostic, prognostic and therapeutic applicability in …

Prostate cancer, version 1.2016

JL Mohler, AJ Armstrong, RR Bahnson… - Journal of the National …, 2016 - jnccn.org
The NCCN Guidelines for Prostate Cancer address staging and risk assessment after an
initial diagnosis of prostate cancer and management options for localized, regional, and …