Oxidative stress (OS), which arises through an imbalance between the formation of reactive
oxygen species (ROS) and antioxidant defenses, plays a key role in the pathophysiology of …

In modern post-transition societies, we are reproducing later and living longer. While the
impact of age on female reproductive function has been well studied, much less is known …

Oxidative stress is a significant factor in male infertility, compromising sperm function and
overall reproductive health. As male infertility garners increasing attention, effective …

Advanced age has been reported to negatively affect sperm parameters and spermatozoa
DNA integrity. A decline in sperm criteria was also associated with altered epigenetic marks …

Background: Non-obstructive azoospermia (NOA) presents a challenge in male infertility
management. This study aimed to assess the efficacy of diagnostic testicular biopsy (DTB) in …

Recent advancements in the understanding of how sperm develop into offspring have
shown complex interactions between environmental influences and genetic factors. The past …

Approximately 80% of miscarriages happen within the first 12 weeks of gestation. More than
half of early losses result from genetic defects, usually presenting as abnormal chromosome …

Infertility is defined as the inability to conceive after at least 12 months of regular,
unprotected sexual intercourse and it is considered an alarming global health issue. More …

Introduction The long interspersed nuclear element-1 (LINE1) gene is a retrotransposon
whose methylation status appears to play a role in spermatogenesis, the outcome of …

Infertility is a global health concern, with male factors playing an especially large role.
Unfortunately, however, the contributions made by reproductive urologists in managing male …