Sex differences in traumatic brain injury: what we know and what we should know
There is growing recognition of the problem of male bias in neuroscience research,
including in the field of traumatic brain injury (TBI) where fewer women than men are …
including in the field of traumatic brain injury (TBI) where fewer women than men are …
[HTML][HTML] Measuring anxiety-like behaviors in rodent models of traumatic brain injury
Anxiety is a common complaint following acquired traumatic brain injury (TBI). However, the
measurement of dysfunctional anxiety behavioral states following experimental TBI in …
measurement of dysfunctional anxiety behavioral states following experimental TBI in …
Sexual dimorphism in the inflammatory response to traumatic brain injury
The activation of resident microglial cells, alongside the infiltration of peripheral
macrophages, are key neuroinflammatory responses to traumatic brain injury (TBI) that are …
macrophages, are key neuroinflammatory responses to traumatic brain injury (TBI) that are …
[HTML][HTML] Vγ1 and Vγ4 gamma-delta T cells play opposing roles in the immunopathology of traumatic brain injury in males
Traumatic brain injury (TBI) is a leading cause of morbidity and mortality. The innate and
adaptive immune responses play an important role in the pathogenesis of TBI. Gamma-delta …
adaptive immune responses play an important role in the pathogenesis of TBI. Gamma-delta …
Sex differences in acute neuroinflammation after experimental traumatic brain injury are mediated by infiltrating myeloid cells
The inflammatory response to moderate-severe controlled cortical impact (CCI) in adult male
mice has been shown to exhibit greater glial activation compared with age-matched female …
mice has been shown to exhibit greater glial activation compared with age-matched female …
[HTML][HTML] Behavior of male and female C57BL/6J mice is more consistent with repeated trials in the elevated zero maze than in the elevated plus maze
The elevated plus maze (EPM) and elevated zero maze (EZM) are behavioral tests that are
widely employed to assess anxiety-like behaviors in rats and mice following experimental …
widely employed to assess anxiety-like behaviors in rats and mice following experimental …
Affective, neurocognitive and psychosocial disorders associated with traumatic brain injury and post-traumatic epilepsy
Survivors of traumatic brain injury (TBI) often develop chronic neurological, neurocognitive,
psychological, and psychosocial deficits that can have a profound impact on an individual's …
psychological, and psychosocial deficits that can have a profound impact on an individual's …
[HTML][HTML] Endocannabinoids: a promising impact for traumatic brain injury
LD Schurman, AH Lichtman - Frontiers in pharmacology, 2017 - frontiersin.org
The endogenous cannabinoid (endocannabinoid) system regulates a diverse array of
physiological processes and unsurprisingly possesses considerable potential targets for the …
physiological processes and unsurprisingly possesses considerable potential targets for the …
[HTML][HTML] Acute colitis during chronic experimental traumatic brain injury in mice induces dysautonomia and persistent extraintestinal, systemic, and CNS inflammation …
Background Disruptions of brain-gut axis have been implicated in the progression of a
variety of gastrointestinal (GI) disorders and central nervous system (CNS) diseases and …
variety of gastrointestinal (GI) disorders and central nervous system (CNS) diseases and …
[HTML][HTML] The closed-head impact model of engineered rotational acceleration (CHIMERA) as an application for traumatic brain injury pre-clinical research: a status …
EH McNamara, AA Grillakis, LB Tucker… - Experimental neurology, 2020 - Elsevier
Closed-head traumatic brain injury (TBI) is a worldwide concern with increasing prevalence
and cost to society. Rotational acceleration is a primary mechanism in TBI that results from …
and cost to society. Rotational acceleration is a primary mechanism in TBI that results from …