[HTML][HTML] Overview of the muscle cytoskeleton
CA Henderson, CG Gomez, SM Novak… - Comprehensive …, 2017 - ncbi.nlm.nih.gov
Cardiac and skeletal striated muscles are intricately designed machines responsible for
muscle contraction. Coordination of the basic contractile unit, the sarcomere, and the …
muscle contraction. Coordination of the basic contractile unit, the sarcomere, and the …
Role of TGF-β signaling in inherited and acquired myopathies
TN Burks, RD Cohn - Skeletal muscle, 2011 - Springer
The transforming growth factor-beta (TGF-β) superfamily consists of a variety of cytokines
expressed in many different cell types including skeletal muscle. Members of this …
expressed in many different cell types including skeletal muscle. Members of this …
Myostatin: Basic biology to clinical application
P Esposito, D Picciotto, Y Battaglia, F Costigliolo… - Advances in clinical …, 2022 - Elsevier
Myostatin is a member of the transforming growth factor (TGF)-β superfamily. It is expressed
by animal and human skeletal muscle cells where it limits muscle growth and promotes …
by animal and human skeletal muscle cells where it limits muscle growth and promotes …
The sarcomeric cytoskeleton: who picks up the strain?
M Gautel - Current opinion in cell biology, 2011 - Elsevier
In striated muscle sarcomeres, the contractile actin and myosin filaments are organised by a
subset of specialised cytoskeletal proteins, the sarcomeric cytoskeleton. They include α …
subset of specialised cytoskeletal proteins, the sarcomeric cytoskeleton. They include α …
The role of Z-disc proteins in myopathy and cardiomyopathy
K Wadmore, AJ Azad, K Gehmlich - International Journal of Molecular …, 2021 - mdpi.com
The Z-disc acts as a protein-rich structure to tether thin filament in the contractile units, the
sarcomeres, of striated muscle cells. Proteins found in the Z-disc are integral for maintaining …
sarcomeres, of striated muscle cells. Proteins found in the Z-disc are integral for maintaining …
Cytoskeletal protein kinases: titin and its relations in mechanosensing
M Gautel - Pflügers Archiv-European Journal of Physiology, 2011 - Springer
Titin, the giant elastic ruler protein of striated muscle sarcomeres, contains a catalytic kinase
domain related to a family of intrasterically regulated protein kinases. The most extensively …
domain related to a family of intrasterically regulated protein kinases. The most extensively …
Genome-wide identification of loci associated with growth in rainbow trout
Background Growth is a major economic production trait in aquaculture. Improvements in
growth performance will reduce time and cost for fish to reach market size. However, genes …
growth performance will reduce time and cost for fish to reach market size. However, genes …
Telethonin deficiency is associated with maladaptation to biomechanical stress in the mammalian heart
Rationale: Telethonin (also known as titin-cap or t-cap) is a 19-kDa Z-disk protein with a
unique β-sheet structure, hypothesized to assemble in a palindromic way with the N-terminal …
unique β-sheet structure, hypothesized to assemble in a palindromic way with the N-terminal …
[HTML][HTML] Juvenile idiopathic arthritis-associated genetic loci exhibit spatially constrained gene regulatory effects across multiple tissues and immune cell types
Juvenile idiopathic arthritis (JIA) is an autoimmune, inflammatory joint disease with complex
genetic etiology. Previous GWAS have found many genetic loci associated with JIA …
genetic etiology. Previous GWAS have found many genetic loci associated with JIA …
CRISPR gene editing in pluripotent stem cells reveals the function of MBNL proteins during human in vitro myogenesis
A Mérien, J Tahraoui-Bories, M Cailleret… - Human molecular …, 2022 - academic.oup.com
Alternative splicing has emerged as a fundamental mechanism for the spatiotemporal
control of development. A better understanding of how this mechanism is regulated has the …
control of development. A better understanding of how this mechanism is regulated has the …