NMR spectroscopy is a powerful tool for biologists interested in the structure, dynamics, and
interactions of biological macromolecules. This review aims at presenting in an accessible …

Abstract Background ACPYPE (or AnteChamber PYthon Parser interfacE) is a wrapper
script around the ANTECHAMBER software that simplifies the generation of small molecule …

Recent advances in high‐throughput experimental techniques have led to an exponential
increase in both the size and the complexity of the data sets commonly studied in biology …

Abstract The WeNMR (http://www. wenmr. eu) project is a European Union funded
international effort to streamline and automate analysis of Nuclear Magnetic Resonance …

Background Recognition of histone modifications by specialized protein domains is a key
step in the regulation of DNA-mediated processes like gene transcription. The structural …

As methods for analysis of biomolecular structure and dynamics using nuclear magnetic
resonance spectroscopy (NMR) continue to advance, the resulting 3D structures, chemical …

G-protein-coupled receptors (GPCRs) are the most important signal transducers in higher
eukaryotes. Despite considerable progress, the molecular basis of subtype-specific ligand …

HnRNP A1 regulates many alternative splicing events by the recognition of splicing silencer
elements. Here, we provide the solution structures of its two RNA recognition motifs (RRMs) …

TA (toxin–antitoxin) systems are widely distributed amongst bacteria and are associated with
the formation of antibiotic tolerant (persister) cells that may have involvement in chronic and …

Alternative pre-messenger ribonucleic acid (pre-mRNA) splicing is an essential process in
eukaryotic gene regulation. The T-cell intracellular antigen-1 (TIA-1) is an apoptosis …