[PDF][PDF] A comprehensive review of the lipid cubic phase or in meso method for crystallizing membrane and soluble proteins and complexes

M Caffrey - Acta Crystallographica Section F: Structural Biology …, 2015 - journals.iucr.org
The lipid cubic phase or in meso method is a robust approach for crystallizing membrane
proteins for structure determination. The uptake of the method is such that it is experiencing …

Transforming X-ray detection with hybrid photon counting detectors

A Förster, S Brandstetter… - … Transactions of the …, 2019 - royalsocietypublishing.org
Hybrid photon counting (HPC) detectors have radically transformed basic research at
synchrotron light sources since 2006. They excel at X-ray diffraction applications in the …

Structural basis for blue-green light harvesting and energy dissipation in diatoms

W Wang, LJ Yu, C Xu, T Tomizaki, S Zhao, Y Umena… - Science, 2019 - science.org
INTRODUCTION Photosynthetic organisms contain light-harvesting antenna systems to
gather light energy required for driving photochemical reactions. Diatoms are a group of …

Structure of the plant photosystem I supercomplex at 2.6 Å resolution

Y Mazor, A Borovikova, I Caspy, N Nelson - Nature plants, 2017 - nature.com
Four elaborate membrane complexes carry out the light reaction of oxygenic photosynthesis.
Photosystem I (PSI) is one of two large reaction centres responsible for converting light …

Structural basis for allosteric ligand recognition in the human CC chemokine receptor 7

K Jaeger, S Bruenle, T Weinert, W Guba, J Muehle… - Cell, 2019 - cell.com
The CC chemokine receptor 7 (CCR7) balances immunity and tolerance by homeostatic
trafficking of immune cells. In cancer, CCR7-mediated trafficking leads to lymph node …

The ancient gamete fusogen HAP2 is a eukaryotic class II fusion protein

J Fedry, Y Liu, G Pehau-Arnaudet, J Pei, W Li… - Cell, 2017 - cell.com
Sexual reproduction is almost universal in eukaryotic life and involves the fusion of male and
female haploid gametes into a diploid cell. The sperm-restricted single-pass transmembrane …

Experimental phasing opportunities for macromolecular crystallography at very long wavelengths

K El Omari, R Duman, V Mykhaylyk, CM Orr… - Communications …, 2023 - nature.com
Despite recent advances in cryo-electron microscopy and artificial intelligence-based model
predictions, a significant fraction of structure determinations by macromolecular …

[HTML][HTML] EIGER detector: application in macromolecular crystallography

A Casanas, R Warshamanage, AD Finke… - … Section D: Structural …, 2016 - scripts.iucr.org
The development of single-photon-counting detectors, such as the PILATUS, has been a
major recent breakthrough in macromolecular crystallography, enabling noise-free detection …

Drug repurposing screen identifies lonafarnib as respiratory syncytial virus fusion protein inhibitor

SM Sake, X Zhang, MK Rajak… - Nature …, 2024 - nature.com
Respiratory syncytial virus (RSV) is a common cause of acute lower respiratory tract
infection in infants, older adults and the immunocompromised. Effective directly acting …

Native phasing of x-ray free-electron laser data for a G protein–coupled receptor

A Batyuk, L Galli, A Ishchenko, GW Han, C Gati… - Science …, 2016 - science.org
Serial femtosecond crystallography (SFX) takes advantage of extremely bright and ultrashort
pulses produced by x-ray free-electron lasers (XFELs), allowing for the collection of high …