Remarkable progress has been made in the development of new therapies for cancer,
dramatically changing the landscape of treatment approaches for several malignancies and …

Human induced pluripotent stem cells (hiPSCs) provide a powerful platform for disease
modeling and have unlocked new possibilities for understanding the mechanisms governing …

Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) have enormous potential
for the study of human cardiac disorders. However, their physiological immaturity severely …

Summary Coronavirus disease 2019 (COVID-19) is a pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is defined by respiratory …

Organoids derived from human pluripotent stem cells are a potentially powerful tool for high-
throughput screening (HTS), but the complexity of organoid cultures poses a significant …

Stem cell transplantation holds great promise as a potential treatment for currently incurable
retinal degenerative diseases that cause poor vision and blindness. Recently, safety data …

Current therapy of advanced cancers is based on several modalities including radiotherapy,
cytotoxic chemotherapy, molecularly targeted inhibitors and antibodies targeting immune …

Rationale: Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) are a readily
available, robustly reproducible, and physiologically appropriate human cell source for …

Induced pluripotent stem cells (iPSCs) offer an unprece-dented opportunity to study human
physiology and disease at the cellular level. They also have the potential to be leveraged in …

Synthetic biology aims to design or assemble existing bioparts or bio-components for useful
bioproperties. During the past decades, progresses have been made to build delicate …