We are in the midst of a shift in biological research paradigms from reductionist
methodologies that generate a hypothesis and rigorously and quantitatively measure the …

The quantification of metabolites in various samples, including body fluids, tissues, cells,
and foodstuffs, contributes to our understanding of their biological activities and roles in the …

Exposome is the future of next-generation environmental health to establish the association
between environmental exposure and diseases. However, due to low concentrations of …

Metabolomics strives to capture the entirety of the metabolites in a biological system by
comprehensive analysis, often by liquid chromatography hyphenated to mass spectrometry …

A novel chiral porous column was fabricated by lipase immobilized MIL-100 (Fe)
biocomposites as chiral stationary phase through covalent coupling and applied to capillary …

Central carbon and energy metabolism are the most concerned metabolic pathways in 13 C-
Metabolic flux analysis (13 C-MFA). However, some α-keto acids, ribonucleoside …

A capillary was co-immobilized with mixed β-cyclodextrin and bovine serum album by
chemical covalent coupling as the chiral stationary phase for the enantioseparation of proton …

Urinary sarcosine was considered to be a potential biomarker for prostate cancer (Pca). In
this work, an integrated strategy of multiplex tags chemical isotope labeling (MTCIL) …

Discrimination of isomers is an important and valuable feature in many analytical
applications, and the identification of chiral isomers and cis–trans isomers is the current …

Chiral analysis of food components can provide important information for food quality,
bioactivity and safety. Determination of enantiomeric ratios in food is a tedious task, due to …