[HTML][HTML] Apoptotic cell death in disease—Current understanding of the NCCD 2023

I Vitale, F Pietrocola, E Guilbaud… - Cell Death & …, 2023 - nature.com
Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase
family. Pharmacological and genetic strategies that experimentally inhibit or delay apoptosis …

NLRP3 inflammasome activation and cell death

Y Huang, W Xu, R Zhou - Cellular & molecular immunology, 2021 - nature.com
The NLRP3 inflammasome is a cytosolic multiprotein complex composed of the innate
immune receptor protein NLRP3, adapter protein ASC, and inflammatory protease caspase …

[HTML][HTML] Diversity and complexity of cell death: a historical review

W Park, S Wei, BS Kim, B Kim, SJ Bae… - … & molecular medicine, 2023 - nature.com
Death is the inevitable fate of all living organisms, whether at the individual or cellular level.
For a long time, cell death was believed to be an undesirable but unavoidable final outcome …

[HTML][HTML] Apoptosis (programmed cell death) and its signals-A review

E Obeng - Brazilian Journal of Biology, 2020 - SciELO Brasil
Apoptosis is a sequential order of cell death occurring regularly to ensure a homeostatic
balance between the rate of cell formation and cell death. However, a misplaced of this …

Reactive oxygen species‐induced lipid peroxidation in apoptosis, autophagy, and ferroptosis

LJ Su, JH Zhang, H Gomez, R Murugan… - Oxidative medicine …, 2019 - Wiley Online Library
Reactive oxygen species‐(ROS‐) induced lipid peroxidation plays a critical role in cell death
including apoptosis, autophagy, and ferroptosis. This fundamental and conserved …

The concept of intrinsic versus extrinsic apoptosis

L Lossi - Biochemical Journal, 2022 - portlandpress.com
Regulated cell death is a vital and dynamic process in multicellular organisms that maintains
tissue homeostasis and eliminates potentially dangerous cells. Apoptosis, one of the better …

[HTML][HTML] Apoptosis deregulation and the development of cancer multi-drug resistance

CM Neophytou, IP Trougakos, N Erin, P Papageorgis - Cancers, 2021 - mdpi.com
Simple Summary Despite recent therapeutic advances against cancer, many patients do not
respond well or respond poorly, to treatment and develop resistance to more than one anti …

[HTML][HTML] Osteoblast-osteoclast communication and bone homeostasis

JM Kim, C Lin, Z Stavre, MB Greenblatt, JH Shim - Cells, 2020 - mdpi.com
Bone remodeling is tightly regulated by a cross-talk between bone-forming osteoblasts and
bone-resorbing osteoclasts. Osteoblasts and osteoclasts communicate with each other to …

[HTML][HTML] Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

L Galluzzi, I Vitale, SA Aaronson, JM Abrams… - Cell Death & …, 2018 - nature.com
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …

[HTML][HTML] Mechanisms for modulating anoikis resistance in cancer and the relevance of metabolic reprogramming

FO Adeshakin, AO Adeshakin, LO Afolabi, D Yan… - Frontiers in …, 2021 - frontiersin.org
The attachment of cells to the extracellular matrix (ECM) is the hallmark of structure–function
stability and well-being. ECM detachment in localized tumors precedes abnormal …