[HTML][HTML] Cell identity changes in ocular surface Epithelia

N Di Girolamo, M Park - Progress in Retinal and Eye Research, 2023 - Elsevier
Corneal and conjunctival epithelia arise from a common ancestral ectoderm cell, then
diverge into distinct lineages. The former develops into a multilayered stratified squamous …

Keratin expression by corneal and limbal stem cells during development

WWY Kao - Experimental eye research, 2020 - Elsevier
Keratins are the forming units of intermediate filaments (IF) that provide mechanical support,
and formation of desmosomes between cells and hemi desmosomes with basement …

Human corneal stromal stem cells support limbal epithelial cells cultured on RAFT tissue equivalents

AK Kureshi, M Dziasko, JL Funderburgh, JT Daniels - Scientific reports, 2015 - nature.com
Human limbal epithelial cells (HLE) and corneal stromal stem cells (CSSC) reside in close
proximity in vivo in the corneal limbal stem cell niche. However, HLE are typically cultured in …

[HTML][HTML] Alterations of epithelial stem cell marker patterns in human diabetic corneas and effects of c-met gene therapy

M Saghizadeh, S Soleymani, A Harounian… - Molecular …, 2011 - ncbi.nlm.nih.gov
Purpose We have previously identified specific epithelial proteins with altered expression in
human diabetic central corneas. Decreased hepatocyte growth factor receptor (c-met) and …

Chitosan–gelatin biopolymers as carrier substrata for limbal epithelial stem cells

A De La Mata, T Nieto-Miguel… - Journal of Materials …, 2013 - Springer
The aim of this work was to evaluate semi-synthetic biopolymers based on chitosan (CH)
and gelatin (G) as potential in vitro carrier substrata for human limbal epithelial cells …

Corneal goblet cells and their niche: implications for corneal stem cell deficiency

A Pajoohesh-Ganji, S Pal-Ghosh, G Tadvalkar… - Stem …, 2012 - academic.oup.com
Goblet cells are terminally differentiated cells secreting mucins and antibacterial peptides
that play an important role in maintaining the health of the cornea. In corneal stem cell …

Cultivation and characterization of cornea limbal epithelial stem cells on lens capsule in animal material-free medium

R Albert, Z Vereb, K Csomos, MC Moe, EO Johnsen… - 2012 - journals.plos.org
A simple, reproducible, animal-material free method for cultivating and characterizing
cornea limbal epithelial stem cells (LESCs) on human lens capsule (LC) was developed for …

Impact of the controlled release of a connexin 43 peptide on corneal wound closure in an STZ model of type I diabetes

K Moore, G Ghatnekar, RG Gourdie, JD Potts - PloS one, 2014 - journals.plos.org
The alpha-carboxy terminus 1 (αCT1) peptide is a synthetically produced mimetic modified
from the DDLEI C-terminus sequence of connexin 43 (Cx43). Previous research using …

Poly-l/dl-lactic acid films functionalized with collagen IV as carrier substrata for corneal epithelial stem cells

A de la Mata, MA Mateos-Timoneda… - Colloids and Surfaces B …, 2019 - Elsevier
Limbal epithelial stem cells (LESCs) are responsible for the renewal of corneal epithelium.
Cultivated limbal epithelial transplantation is the current treatment of choice for restoring the …

Vimentin as a marker of early differentiating, highly motile corneal epithelial cells

F Castro‐Muñozledo, DG Meza‐Aguilar… - Journal of cellular …, 2017 - Wiley Online Library
Vimentin (Vim), a cytoskeletal intermediate filament, is part of a naturally occurring reversible
program, the Epithelial‐Mesenchymal Transition (EMT), which converts epithelial cells into …