Aptamer–protein interactions: from regulation to biomolecular detection

C Ji, J Wei, L Zhang, X Hou, J Tan, Q Yuan… - Chemical …, 2023 - ACS Publications
Serving as the basis of cell life, interactions between nucleic acids and proteins play
essential roles in fundamental cellular processes. Aptamers are unique single-stranded …

State of the art in CRISPR/Cas system-based signal conversion and amplification applied in the field of food analysis

B Lu, Z Guo, K Zhong, T Osire, Y Sun, L Jiang - Trends in Food Science & …, 2023 - Elsevier
Background Food safety is a major global public health issue. The majority of traditional
culture-based methods have lengthy detection times, require sophisticated sample …

Self-assembling nucleic acid nanostructures functionalized with aptamers

A Krissanaprasit, CM Key, S Pontula… - Chemical …, 2021 - ACS Publications
Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …

Functional nucleic acid-based hydrogels for bioanalytical and biomedical applications

J Li, L Mo, CH Lu, T Fu, HH Yang, W Tan - Chemical Society Reviews, 2016 - pubs.rsc.org
Hydrogels are crosslinked hydrophilic polymers that can absorb a large amount of water. By
their hydrophilic, biocompatible and highly tunable nature, hydrogels can be tailored for …

Chemistry, biology, and medicine of fluorescent nanomaterials and related systems: new insights into biosensing, bioimaging, genomics, diagnostics, and therapy

J Yao, M Yang, Y Duan - Chemical reviews, 2014 - ACS Publications
2. INTRODUCTION The investigation of many fundamental processes in life sciences
requires straightforward tools for fast, sensitive, reliable, and reproducible detection of …

Investigations on the interface of nucleic acid aptamers and binding targets

S Cai, J Yan, H Xiong, Y Liu, D Peng, Z Liu - Analyst, 2018 - pubs.rsc.org
Nucleic acid aptamers are single-stranded DNA or RNA of 20–100 nucleotides in length that
have attracted substantial scientific interest due to their ability to specifically bind to target …

Aptamer-based biosensors for biomedical diagnostics

W Zhou, PJJ Huang, J Ding, J Liu - Analyst, 2014 - pubs.rsc.org
Aptamers are single-stranded nucleic acids that selectively bind to target molecules. Most
aptamers are obtained through a combinatorial biology technique called SELEX. Since …

Ultrasensitive aptamer-functionalized Cu-MOF fluorescent nanozyme as an optical biosensor for detection of C-reactive protein

GK Ali, KM Omer - Analytical biochemistry, 2022 - Elsevier
In the present work, an aptasensing method based on integration of RNA on Cu-MOF was
developed for detection of C-Reactive Protein (CRP). Cu-MOF showed stimulated …

Surface modification, functionalization and bioconjugation of colloidal inorganic nanoparticles

RA Sperling, WJ Parak - Philosophical Transactions of …, 2010 - royalsocietypublishing.org
Inorganic colloidal nanoparticles are very small, nanoscale objects with inorganic cores that
are dispersed in a solvent. Depending on the material they consist of, nanoparticles can …

Aptamers from cell-based selection for bioanalytical applications

W Tan, MJ Donovan, J Jiang - Chemical reviews, 2013 - ACS Publications
Nucleic acids are the foundation of life. Specific sequences translate certain genetic traits,
protein expression, and, ultimately, cellular function. Yet, nucleic acids not only store genetic …