The bioprinting of heterogeneous organs is a crucial issue. To reach the complexity of such
organs, there is a need for highly specialized software that will meet all requirements such …

Most of the 3D breast tumor models used in drug screening studies only comprise tumor
cells, keeping out other essential cell players of the tumor microenvironment. Tumor …

Au-Fe3O4 nanoheterodimers (NHD) were functionalized with the natural and synthetic
anticancer drugs caffeic acid (CA), quercetin (Q) and 5-fluorocytidine (5FC). Their X …

This study presents an improved method for obtaining spheroids microwell arrays for
histological processing and analysis, focusing on glioblastoma (U87 MG) and breast …

Three-dimensional cell spheroid models can be used to predict the effect of drugs and
therapeutics and to model tissue development and regeneration. The utility of these models …

Enhanced drug testing efficiency has driven the prominence of high-content (HC) and high-
throughput (HT) screening (HCHTS) in drug discovery and development. However …

Tissue engineering strategies using microtissues as “building blocks” have high potential in
regenerative medicine. Cognition of contraction dynamics involved in the in vitro self …

Organoids can recapitulate human-specific phenotypes and functions in vivo and have great
potential for research in development, disease modeling, and drug screening. Due to the …

Microfluidic devices utilizing spheroids play important roles in in vitro experimental systems
to closely simulate morphological and biochemical characteristics of the in vivo tumor …

Background and objective A key factor in the modulation of angiogenesis as well as in bone
resorption is angiopoietin‐like 4. However, the role of angiopoietin‐like 4 in periodontal …