[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives
H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …
Leveraging self-assembled nanobiomaterials for improved cancer immunotherapy
Nanomaterials and targeted drug delivery vehicles improve the therapeutic index of drugs
and permit greater control over their pharmacokinetics, biodistribution, and bioavailability …
and permit greater control over their pharmacokinetics, biodistribution, and bioavailability …
Promoting Re-epithelialization in an oxidative diabetic wound microenvironment using self-assembly of a ROS-responsive polymer and P311 peptide micelles
R Shi, H Li, X Jin, X Huang, Z Ou, X Zhang, G Luo… - Acta Biomaterialia, 2022 - Elsevier
Engineering smart nano-therapeutics for re-epithelialisation of chronic wounds facilitates the
wound healing process. However, due to excessive oxidative stress damage and persistent …
wound healing process. However, due to excessive oxidative stress damage and persistent …
An insight on ophthalmic drug delivery systems: focus on polymeric biomaterials-based carriers
Presently, different types of eye diseases, such as glaucoma, myopia, infection, and dry eyes
are treated with topical eye drops. However, due to ocular surface barriers, eye drops …
are treated with topical eye drops. However, due to ocular surface barriers, eye drops …
Breaking barriers in eye treatment: Polymeric nano-based drug-delivery system for anterior segment diseases and glaucoma
The eye has anatomical structures that function as robust static and dynamic barriers,
limiting the penetration, residence time, and bioavailability of medications administered …
limiting the penetration, residence time, and bioavailability of medications administered …
Assessing the Steric Impact of Surface Ligands on the Proteolytic Turnover of Quantum Dot–Peptide Conjugates
Proteases are important biomarkers and targets for the diagnosis and treatment of disease.
The advantageous properties of semiconductor quantum dots (QDs) have made these …
The advantageous properties of semiconductor quantum dots (QDs) have made these …
Harnessing the therapeutic potential of biomacromolecules through intracellular delivery of nucleic acids, peptides, and proteins
Biomacromolecules have long been at the leading edge of academic and pharmaceutical
drug development and clinical translation. With the clinical advances of new therapeutics …
drug development and clinical translation. With the clinical advances of new therapeutics …
Nanocarriers for targeted drug delivery in the vascular system: Focus on endothelium
X Cong, Z Zhang, H Li, YG Yang, Y Zhang… - Journal of …, 2024 - Springer
Endothelial cells (ECs) are pivotal in maintaining vascular health, regulating hemodynamics,
and modulating inflammatory responses. Nanocarriers hold transformative potential for …
and modulating inflammatory responses. Nanocarriers hold transformative potential for …
Nanomaterials in the diagnosis and treatment of ophthalmic diseases
Y Ma, Z Zhang, Y Yu, X Wang, S Liu, B Sun, Z Cai… - Nano Today, 2024 - Elsevier
The complexity of the human eye structure poses challenges in the diagnosis and treatment
of ocular diseases, especially the low efficiency of ocular drug delivery. With the continuous …
of ocular diseases, especially the low efficiency of ocular drug delivery. With the continuous …
Fostering the unleashing potential of nanocarriers-mediated delivery of ocular therapeutics
Ocular delivery is the most challenging aspect in the field of pharmaceutical research. The
major hurdle for the controlled delivery of drugs to the eye includes the physiological static …
major hurdle for the controlled delivery of drugs to the eye includes the physiological static …