Mechanisms of action and persistent neuroplasticity by drugs of abuse

ER Korpi, B den Hollander, U Farooq… - Pharmacological …, 2015 - Elsevier
Adaptation of the nervous system to different chemical and physiologic conditions is
important for the homeostasis of brain processes and for learning and remembering …

Role of mitochondria in methamphetamine-induced dopaminergic neurotoxicity: involvement in oxidative stress, neuroinflammation, and pro-apoptosis—a review

EJ Shin, HQ Tran, PT Nguyen, JH Jeong, SY Nah… - Neurochemical …, 2018 - Springer
Abstract Methamphetamine (MA), an amphetamine-type psychostimulant, is associated with
dopaminergic toxicity and has a high abuse potential. Numerous in vivo and in vitro studies …

Raising awareness of new psychoactive substances: chemical analysis and in vitro toxicity screening of 'legal high'packages containing synthetic cathinones

AM Araújo, MJ Valente, M Carvalho… - Archives of …, 2015 - Springer
The world's status quo on recreational drugs has dramatically changed in recent years due
to the rapid emergence of new psychoactive substances (NPS), represented by new narcotic …

Methamphetamine-induced toxicity: an updated review on issues related to hyperthermia

RR Matsumoto, MJ Seminerio, RC Turner… - Pharmacology & …, 2014 - Elsevier
Reports of methamphetamine-related emergency room visits suggest that elevated body
temperature is a universal presenting symptom, with lethal overdoses generally associated …

Neurotoxicity of β-keto amphetamines: deathly mechanisms elicited by methylone and MDPV in human dopaminergic SH-SY5Y cells

MJ Valente, ML Bastos, E Fernandes… - ACS chemical …, 2017 - ACS Publications
Synthetic cathinones (β-keto amphetamines) act as potent CNS stimulants similarly to
classical amphetamines, which raise concerns about their potential neurotoxic effects. The …

Protective ability against oxidative stress of brewers' spent grain protein hydrolysates

EF Vieira, DD da Silva, H Carmo, IM Ferreira - Food Chemistry, 2017 - Elsevier
The protein fraction of Brewers' spent grain (BSG) was used as substrate to obtain
hydrolysates with antioxidant activity. Three enzymatic approaches were applied: brewer's …

3, 4-Methylenedioxypyrovalerone (MDPV): in vitro mechanisms of hepatotoxicity under normothermic and hyperthermic conditions

MJ Valente, AM Araújo, R Silva, ML Bastos… - Archives of …, 2016 - Springer
Synthetic cathinones have emerged in recreational drug markets as legal alternatives for
classical amphetamines. Though currently banned in several countries, 3, 4 …

Effects of acute metaphedrone exposure on the development, behaviour, and DNA integrity of zebrafish (Danio rerio)

O Ribeiro, C Ribeiro, L Félix, I Gaivão… - … Science and Pollution …, 2023 - Springer
The presence of new psychoactive substances (NPS), like metaphedrone (3-MMC), in
aquatic environments raises concern about the potential negative effects on ichthyofauna …

The novel psychoactive substance 3-methylmethcathinone (3-MMC or metaphedrone): a review

B Ferreira, DD da Silva, F Carvalho… - Forensic science …, 2019 - Elsevier
Methylmethcathinone (3-MMC or metaphedrone) is a synthetic cathinone, recently
introduced in the market of the new psychoactive substances (NPS), initially to replace …

Mitochondria: key players in the neurotoxic effects of amphetamines

DJ Barbosa, JP Capela, R Feio-Azevedo… - Archives of …, 2015 - Springer
Amphetamines are a class of psychotropic drugs with high abuse potential, as a result of
their stimulant, euphoric, emphathogenic, entactogenic, and hallucinogenic properties …