Optimizing the outcomes of pancreatic cancer surgery

O Strobel, J Neoptolemos, D Jaeger… - Nature reviews Clinical …, 2019 - nature.com
Pancreatic cancer is likely to become the second most frequent cause of cancer-associated
mortality within the next decade. Surgical resection with adjuvant systemic chemotherapy …

The current treatment paradigm for pancreatic ductal adenocarcinoma and barriers to therapeutic efficacy

DR Principe, PW Underwood, M Korc… - Frontiers in …, 2021 - frontiersin.org
Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis, with a median survival
time of 10-12 months. Clinically, these poor outcomes are attributed to several factors …

'Artery-first'approaches to pancreatoduodenectomy

P Sanjay, K Takaori, S Govil… - Journal of British …, 2012 - academic.oup.com
Background The technique of pancreatoduodenectomy (PD) has evolved. Previously, non-
resectability was determined by involvement of the portal vein–superior mesenteric vein …

Pancreatic cancer: An update on diagnosis and management

BPT Loveday, L Lipton… - Australian journal of …, 2019 - search.informit.org
Background: Pancreatic cancer has the highest mortality rate among all main cancer types
and is the fourth leading cause of cancer death in Australia. Objective: This review focuses …

Technical advances in surgery for pancreatic cancer

M Schneider, T Hackert, O Strobel… - British Journal of …, 2021 - academic.oup.com
Background Multimodal treatment concepts enhance options for surgery in locally advanced
pancreatic ductal adenocarcinoma (PDAC). This review provides an overview of technical …

Vascular resection for pancreatic cancer: 2019 French recommendations based on a literature review from 2008 to 6-2019

JR Delpero, A Sauvanet - Frontiers in Oncology, 2020 - frontiersin.org
Introduction: Vascular resection remains a subject of debate in the management of
Pancreatic Ductal Adenocarcinoma (PDAC). These French recommendations were drafted …

Pancreatic resection for cancer—the Heidelberg technique

M Schneider, O Strobel, T Hackert… - Langenbeck's archives of …, 2019 - Springer
Background Pancreatic cancer is associated with high recurrence rates, and any surgery
should aim to prevent local recurrence. However, systematic resection of putatively tumor …

[HTML][HTML] Curing pancreatic cancer

B Traub, KH Link, M Kornmann - Seminars in cancer biology, 2021 - Elsevier
The distinct biology of pancreatic cancer with aggressive and early invasive tumor cells, a
tumor promoting microenvironment, late diagnosis, and high therapy resistance poses major …

Local radicality and survival outcome of pancreatic cancer surgery

W Niesen, T Hank, M Büchler… - Annals of …, 2019 - Wiley Online Library
Pancreatic cancer remains a therapeutic challenge. Surgical resection in combination with
systemic chemotherapy is the only option promising long‐term survival and potential cure …

Does the artery-first approach improve the rate of R0 resection in pancreatoduodenectomy?: a multicenter, randomized, controlled trial

L Sabater, E Cugat, A Serrablo… - Annals of …, 2019 - journals.lww.com
Objective: To compare the rates of R0 resection in pancreatoduodenectomy (PD) for
pancreatic and periampullary malignant tumors by means of standard (ST-PD) versus artery …