A decade in prostate cancer: from NMR to metabolomics

EM DeFeo, CL Wu, WS McDougal… - Nature Reviews Urology, 2011 - nature.com
Over the past 30 years, continuous progress in the application of nuclear magnetic
resonance (NMR) spectroscopy and magnetic resonance spectroscopic imaging (MRSI) to …

High‐resolution NMR spectroscopy of human body fluids and tissues in relation to prostate cancer

V Kumar, DK Dwivedi, NR Jagannathan - NMR in Biomedicine, 2014 - Wiley Online Library
High‐resolution NMR spectroscopic studies of prostate tissue extracts, prostatic fluid,
seminal fluid, serum and urine can be used for the detection of prostate cancer, based on …

Magnetic Resonance of 2-Hydroxyglutarate in IDH1-Mutated Low-Grade Gliomas

A Elkhaled, LE Jalbert, JJ Phillips… - Science translational …, 2012 - science.org
Recent studies have indicated that a significant survival advantage is conferred to patients
with gliomas whose lesions harbor mutations in the genes isocitrate dehydrogenase 1 and 2 …

Metabolic Profiling of IDH Mutation and Malignant Progression in Infiltrating Glioma

LE Jalbert, A Elkhaled, JJ Phillips, E Neill, A Williams… - Scientific reports, 2017 - nature.com
Infiltrating low grade gliomas (LGGs) are heterogeneous in their behavior and the strategies
used for clinical management are highly variable. A key factor in clinical decision-making is …

Characterization of metabolites in infiltrating gliomas using ex vivo 1H high‐resolution magic angle spinning spectroscopy

A Elkhaled, L Jalbert, A Constantin… - NMR in …, 2014 - Wiley Online Library
Gliomas are routinely graded according to histopathological criteria established by the
World Health Organization. Although this classification can be used to understand some of …

Response of Degarelix treatment in human prostate cancer monitored by HR-MAS 1H NMR spectroscopy

B Madhu, GL Shaw, AY Warren, DE Neal, JR Griffiths - Metabolomics, 2016 - Springer
Introduction The androgen receptor (AR) is the master regulator of prostate cancer cell
metabolism. Degarelix is a novel gonadotrophin-releasing hormone blocker, used to …

Chemical-shift-encoded magnetic resonance imaging and spectroscopy to reveal immediate and long-term multi-organs composition changes of a 14-days periodic …

M Viallon, B Leporq, S Drinda… - Frontiers in …, 2019 - frontiersin.org
Objectives: The aim of this study was to investigate the feasibility of measuring the effects of
a 14-day Periodic Fasting (PF) intervention (< 200 cal) on multi-organs of primary interest …

Creatine, glutamine plus glutamate, and macromolecules are decreased in the central white matter of premature neonates around term

M Koob, A Viola, Y Le Fur, P Viout, H Ratiney… - PLoS …, 2016 - journals.plos.org
Preterm birth represents a high risk of neurodevelopmental disabilities when associated with
white-matter damage. Recent studies have reported cognitive deficits in children born …

Novel role of Tieg1 in muscle metabolism and mitochondrial oxidative capacities

M Kammoun, J Piquereau… - Acta …, 2020 - Wiley Online Library
Aim Tieg1 is involved in multiple signalling pathways, human diseases, and is highly
expressed in muscle where its functions are poorly understood. Methods We have utilized …

Recent advances in metabolic profiling and imaging of prostate cancer

R Thapar, MA Titus - Current Metabolomics, 2014 - ingentaconnect.com
Tumor progression and metastasis are linked to cellular metabolism. Cancer cells, being
highly proliferative, show significant alterations in metabolic pathways such as glycolysis …