Metal‐based nanomaterials have attracted broad attention recently due to their unique
biological physical and chemical properties after entering tumor cells, namely biological …

Calcium ion is vital for the regulation of many cellular functions and serves as a second
messenger in the signal transduction pathways. Once the intracellular Ca2+ level exceeds …

Pyroptosis provides a new direction and broad prospects for cancer immunotherapy.
However, the development of a nanoplatform as a pyroptosis inducer is limited, and the …

Subcellular organelle‐targeted nanoformulations for cancer theranostics are receiving
increasing attention owing to their benefits of precise drug delivery, maximized therapeutic …

Pyroptosis, which is a mode of programmed cell death, has proven effective for cancer
therapy. However, efficient pyroptosis inducers for tumor treatment are limited. This study …

Pyroptosis is an inflammatory form of programmed cell death that holds great promise in
cancer therapy. However, autophagy as the crucial pyroptosis checkpoint and the self …

Although more attention has been attracted to the therapy based on reactive oxygen species
(ROS) for tumor therapy in recent years, such as photodynamic therapy and chemodynamic …

Cancer immunotherapy that deploys the host's immune system to recognize and attack
tumors, is a promising strategy for cancer treatment. However, its efficacy is greatly restricted …

The regulation of intracellular ions' overload to interrupt normal bioprocesses and cause cell
death has been developed as an efficient strategy (named as ion-interference therapy/IIT) to …

Although immunotherapy has a broad clinical application prospect, it is still hindered by low
immune responses and immunosuppressive tumor microenvironment. Herein, a simple and …