Chronic diseases have become one of the most important public health problems, due to
their high costs for treatment and prevention. Until now, researchers have considered that …

Metabolic tissues, including skeletal muscle, adipose tissue and the digestive system,
dynamically secrete various factors depending on the metabolic state, communicate with …

Adipose tissue is a highly active endocrine organ that secrets many pro-inflammatory as well
anti-inflammatory adipokines. The aim of the study was to assess serum adipokine profile in …

Effect of peripheral cannabinoid receptor 1 (CB1R) blockade by AM6545 in the monosodium
glutamate (MSG)-induced hypometabolic and hypothalamic obesity was observed, and the …

Background Polycystic ovary syndrome (PCOS) is frequently associated with
hypovitaminosis D. Vitamin D is endowed with pleiotropic effects, including insulin …

Retinol binding protein 4 (RBP4), a novel cytokine, is mainly secreted by hepatocytes and
adipocytes. RBP4 reportedly induces insulin resistance and RBP4 secretion is increased in …

Patients with obesity are susceptible to hypertension and diabetes. Over-activation of
cannabinoid receptor 1 (CB1R) in adipose tissue is proposed in the pathophysiology of …

Aims Aim of the present study was to investigate the effect of co-administration coenzyme
Q10 and pioglitazone on the mRNA expression of adipocytokines in white adipose tissues of …

The process of preadipocytes differentiation plays a vital role in adipose tissue expansion
and many factors are involved in this event. Cathepsin B (CTSB), secreted from lysosome …

Background: Statins cannot be used for some active liver diseases, which limits its
application to some extent. The combined use of statins with other drugs may be one of the …