Conspectus Transition-metal-catalyzed reductive coupling of electrophiles has emerged as
a powerful tool for the construction of molecules. While major achievements have been …

The development of late-stage functionalization (LSF) methodologies, particularly C–H
functionalization, has revolutionized the field of organic synthesis. Over the past decade …

Conspectus Transition-metal catalyzed cross-coupling reactions are fundamental reactions
in organic chemistry, facilitating strategic bond formations for accessing natural products …

Cross-coupling platforms are traditionally built around a sequence of closed-shell steps,
such as oxidative addition, transmetalation, and reductive elimination. Herein, we describe a …

Quaternary carbons are ubiquitous in bioactive molecules; however, synthetic methods for
the construction of this motif remain underdeveloped. Here, we report the synthesis of …

Polypyridine-ligated nickel complexes are widely used as privileged catalysts in a variety of
cross-coupling reactions. The rapid adoption of these complexes is tentatively attributed to …

Disproportionation and comproportionation reactions have become increasingly important
electron transfer events in organometallic chemistry and catalysis. The renewed interest in …

Alcohols and carboxylic acids are among the most commercially abundant, synthetically
versatile, and operationally convenient functional groups in organic chemistry. Under visible …

Alcohols are commercially abundant and structurally diverse reservoirs of sp3-hybridized
chemical space. However, the direct utilization of alcohols in C–C bond-forming cross …

Sulfinates are important lynchpin intermediates in pharmaceutical production; however, their
synthesis via photoredox catalysis is challenging because of their facile oxidation. We …