Functional constipation is common in children and adults worldwide. Functional constipation
shows similarities in children and adults, but important differences also exist regarding …

Constipation is a common and burdensome gastrointestinal disorder that may result from
altered gastrointestinal motility. The effect of probiotics on constipation has been …

Constipation is a common symptom that may be primary (idiopathic or functional) or
associated with a number of disorders or medications. Although most constipation is self …

Chronic idiopathic constipation (CIC) is one of the most common gastrointestinal disorders,
with a global prevalence of 14%. It is commoner in women and its prevalence increases with …

Our understanding of human colonic motility, and autonomic reflexes that generate motor
patterns, has increased markedly through high-resolution manometry. Details of the motor …

Background Over the last few years, the study of the colon and anorectal function has
experienced great technical advances that have facilitated the performance of the tests and …

In recent years there have been significant technical and methodological advances in our
ability to record the movements of the gastrointestinal tract. This has led to significant …

Objectives: Sacral nerve stimulation (SNS) is a potential treatment for constipation refractory
to standard therapies. However, there have been no randomized controlled studies …

ABSTRACT BACKGROUND Chronic constipation is a prevalent disorder that affects
patients' quality of life and consumes resources in healthcare systems worldwide. In clinical …

Colonic cyclic motor patterns (CMPs) have been hypothesized to act as a brake to limit rectal
filling. However, the spatiotemporal profile of CMPs, including anatomic origins and …