The complexity and heterogeneity of schizophrenia symptoms challenge an objective
diagnosis, which is typically based on behavioral and clinical manifestations. Moreover, the …

Schizophrenia seems to be a heterogeneous disorder. Emerging evidence indicates that
low level neuroinflammation (LLNI) may not occur infrequently. Many infectious agents with …

Psychotic disorders affect 3% of the population at some stage in life, are a leading cause of
disability, and impose a great economic burden on society. Major breakthroughs in the …

Introduction: As endophenotypes bridge the gap between genetics and phenotypic disease
expression, identifying reliable markers is important for fostering understanding of …

Background Genome-wide scans have uncovered rare copy number variants conferring
high risk of psychiatric disorders. The 15q13. 3 microdeletion is associated with a …

Cognitive dysfunctions represent a core feature of schizophrenia-spectrum disorders due to
their presence throughout different illness stages and their impact on functioning …

Cognitive impairment is an important aspect of schizophrenia, where cognitive remediation
therapy (CRT) is a promising treatment for improving cognitive functioning. While …

Deep learning techniques have been applied to electroencephalogram (EEG) signals, with
promising applications in the field of psychiatry. Schizophrenia is one of the most disabling …

Both, pharmacological and genome-wide association studies suggest N-methyl-D-aspartate
receptor (NMDAR) dysfunction and excitatory/inhibitory (E/I)-imbalance as a major …

N-methyl-D-aspartate (NMDA) receptor hypofunction leading to neural network dysfunction
is thought to play an important role in the pathophysiology of cognitive impairment …