The Prognostic and therapeutic value and clinical implications of fibroblast activation protein-α as a novel biomarker in colorectal cancer

Z Kalaei, R Manafi-Farid, B Rashidi, FK Kiani… - Cell Communication and …, 2023 - Springer
The identification of contributing factors leading to the development of Colorectal Cancer
(CRC), as the third fatal malignancy, is crucial. Today, the tumor microenvironment has been …

From glioma gloom to immune bloom: unveiling novel immunotherapeutic paradigms-a review

M Regmi, Y Wang, W Liu, Y Dai, S Liu, K Ma… - Journal of Experimental …, 2024 - Springer
In tumor therapeutics, the transition from conventional cytotoxic drugs to targeted molecular
therapies, such as those targeting receptor tyrosine kinases, has been pivotal. Despite this …

Artificial intelligence and radiation effects on brain tissue in glioblastoma patient: Preliminary data using a quantitative tool

D Franco, V Granata, R Fusco, R Grassi, V Nardone… - La radiologia …, 2023 - Springer
Purpose The quantification of radiotherapy (RT)-induced functional and morphological brain
alterations is fundamental to guide therapeutic decisions in patients with brain tumors. The …

The Development of Immunotherapy for the Treatment of Recurrent Glioblastoma

X Liu, Z Zhao, W Dai, K Liao, Q Sun, D Chen, X Pan… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma (GBM) is the deadliest primary central nervous system (CNS)
cancer in adults despite aggressive treatment. Once progressed, the prognosis is very poor …

Mechanisms, combination therapy, and biomarkers in cancer immunotherapy resistance

M Yang, M Cui, Y Sun, S Liu, W Jiang - Cell Communication and Signaling, 2024 - Springer
Anti-programmed death 1/programmed death ligand 1 (anti-PD-1/PD-L1) antibodies exert
significant antitumor effects by overcoming tumor cell immune evasion and reversing T-cell …

Predictive value of procollagen c-protease enhancer protein on the prognosis of glioma patients

L Yu, X Hu, H Zhu - Heliyon, 2024 - cell.com
Procollagen c-protease enhancer protein (PCOLCE) performs an essential action in
improving the recreation of procollagen c-protease and promoting the reconstruction of …

Personalized Immunotherapy of Patients: Defining by Single-cell RNA-seq with Artificial Intelligence

B Li - Medical research archives, 2023 - esmed.org
Immunotherapy, including immune cell therapy and targeted therapy, is gradually developed
through the ongoing discovery of molecular compounds or immune cells. Choosing the best …

Genetyczne i molekularne podłoża rozwoju glejaka

P Panek, A Jezela-Stanek - Postępy Biochemii, 2023 - postepybiochemii.ptbioch.edu.pl
Glejak IV stopnia jest najczęściej diagnozowanym i jednocześnie najgorzej rokującym
nowotworem ośrodkowego układu nerwowego (OUN). Pacjenci chorujący na ten rodzaj …