A state-of-the-art review on the MicroRNAs roles in hematopoietic stem cell aging and longevity
GGR Ortiz, Y Mohammadi, A Nazari… - Cell Communication and …, 2023 - Springer
Aging is a biological process determined through time-related cellular and functional
impairments, leading to a decreased standard of living for the organism. Recently, there has …
impairments, leading to a decreased standard of living for the organism. Recently, there has …
Emerging role of stem cell-derived extracellular microRNAs in age-associated human diseases and in different therapies of longevity
Organismal aging involves the progressive decline in organ function and increased
susceptibility to age-associated diseases. This has been associated with the aging of stem …
susceptibility to age-associated diseases. This has been associated with the aging of stem …
miRNA-21 promotes osteogenesis via the PTEN/PI3K/Akt/HIF-1α pathway and enhances bone regeneration in critical size defects
C Yang, X Liu, K Zhao, Y Zhu, B Hu, Y Zhou… - Stem cell research & …, 2019 - Springer
Background Functional reconstruction of maxillofacial bone defects is a considerable clinical
challenge. Many studies have emphasized the osteogenic and angiopoietic abilities of stem …
challenge. Many studies have emphasized the osteogenic and angiopoietic abilities of stem …
Hypoxic preconditioning rejuvenates mesenchymal stem cells and enhances neuroprotection following intracerebral hemorrhage via the miR-326-mediated …
J Liu, J He, L Ge, H Xiao, Y Huang, L Zeng… - Stem cell research & …, 2021 - Springer
Background Intracerebral hemorrhage (ICH) is a major public health concern, and
mesenchymal stem cells (MSCs) hold great potential for treating ICH. However, the quantity …
mesenchymal stem cells (MSCs) hold great potential for treating ICH. However, the quantity …
Inhibition of miR-199a-5p rejuvenates aged mesenchymal stem cells derived from patients with idiopathic pulmonary fibrosis and improves their therapeutic efficacy in …
L Shi, Q Han, Y Hong, W Li, G Gong, J Cui… - Stem Cell Research & …, 2021 - Springer
Background Idiopathic pulmonary fibrosis (IPF) is an age-related disease with no cure.
Mesenchymal stem cell (MSC)-based therapy has emerged as a novel strategy for IPF …
Mesenchymal stem cell (MSC)-based therapy has emerged as a novel strategy for IPF …
The whole profiling and competing endogenous RNA network analyses of noncoding RNAs in adipose-derived stem cells from diabetic, old, and young patients
S Ren, H Xiong, J Chen, X Yang, Y Liu, J Guo… - Stem Cell Research & …, 2021 - Springer
Background Mesenchymal stem cells including adipose-derived stem cells (ASCs) have a
considerable potential in the field of translational medicine. Unfortunately, multiple factors …
considerable potential in the field of translational medicine. Unfortunately, multiple factors …
[HTML][HTML] MiR-1292 targets FZD4 to regulate senescence and osteogenic differentiation of stem cells in TE/SJ/mesenchymal tissue system via the Wnt/β-catenin …
J Fan, X An, Y Yang, H Xu, L Fan, L Deng, T Li… - Aging and …, 2018 - ncbi.nlm.nih.gov
With the expansion of the elderly population, age-related osteoporosis and the resulting
bone loss have become a significant health and socioeconomic issue. In Triple Energizer …
bone loss have become a significant health and socioeconomic issue. In Triple Energizer …
The RNA world of human ageing
JC Gomez-Verjan, ER Vazquez-Martinez… - Human genetics, 2018 - Springer
Ageing is one of the most complex processes in nature; how could we prevent the
associated biological changes and chronic diseases that string along with this process, is a …
associated biological changes and chronic diseases that string along with this process, is a …
[HTML][HTML] Oxidative stress down-regulates MiR-20b-5p, MiR-106a-5p and E2F1 expression to suppress the G1/S transition of the cell cycle in multipotent stromal cells
Oxidative stress has been linked to senescence and tumorigenesis via modulation of the cell
cycle. Using a hydrogen peroxide (H 2 O 2)-induced oxidative stress-induced premature …
cycle. Using a hydrogen peroxide (H 2 O 2)-induced oxidative stress-induced premature …
BCL2L13: physiological and pathological meanings
F Meng, N Sun, D Liu, J Jia, J Xiao, H Dai - Cellular and Molecular Life …, 2021 - Springer
Abstract BCL2L13 is a BCL2-like protein. It has been discovered for two decades, now on
the way to be a hotspot of research with its physiological and pathological meanings found …
the way to be a hotspot of research with its physiological and pathological meanings found …