Emerging evidences show that changes in tumor stroma can adapt cancer cells to
radiotherapy, thereby leading to a reduction in tumor response to treatment. On the other …

Fibrosis is characterized by excessive deposition of extracellular matrix components such as
collagen in tissues or organs. Fibrosis can develop in the heart, kidneys, liver, skin or any …

Cancer remains the leading cause of death around the world. In cancer treatment, over 50%
of cancer patients receive radiotherapy alone or in multimodal combinations with other …

Baicalin is an important flavonoid compound THAT is isolated from the Scutellaria
baicalensis Georgi Chinese herb and plays a critical role in anti‑oxidative, anti‑inflammatory …

It is well known that mast cells (MCs) initiate type I allergic reactions and inflammation in a
quick response to the various stimulants, including—but not limited to—allergens, pathogen …

The biocatalytic activity of transglutaminases (TGs) leads to the synthesis of new covalent
isopeptide bonds (crosslinks) between peptide-bound glutamine and lysine residues, but …

Radiation-induced pulmonary fibrosis (RIPF) is a common complication in patients with lung
cancer and breast cancer after receiving thoracic radiotherapy. The average incidence of …

The syndecans are the major family of transmembrane proteoglycans, usually bearing
multiple heparan sulfate chains. They are present on virtually all nucleated cells of …

Fibrosis is the main cause of limited range of motion (ROM) of shoulder in patients with
frozen shoulder (FS). Overexpression of Interleukin 6 (IL-6) has been correlated with …

Rationale: CD148/PTRJ (receptor-like protein tyrosine phosphatase η) exerts antifibrotic
effects in experimental pulmonary fibrosis via interactions with its ligand syndecan-2; …