HIV therapy—the state of art

D Looney, A Ma, S Johns - The Future of HIV-1 Therapeutics: Resistance …, 2015 - Springer
HIV Attachment. In this cross section, HIV is shown at the top and a target cell is shown at the
bottom in blues. HIV envelope protein (A) has bound to the receptor CD4 (B) and then to …

Next generation sequencing improves detection of drug resistance mutations in infants after PMTCT failure

RG Fisher, DM Smith, B Murrell, R Slabbert… - Journal of Clinical …, 2015 - Elsevier
Background Next generation sequencing (NGS) allows the detection of minor variant HIV
drug resistance mutations (DRMs). However data from new NGS platforms after Prevention …

[PDF][PDF] Minority HIV-1 drug-resistant mutations and prevention of mother-to-child transmission: perspectives for resource-limited countries

R Samuel, R Paredes, R Parboosing, P Moodley… - AIDS Rev, 2014 - researchgate.net
The detection and clinical significance of HIV-1 minority drug-resistant variants is a major
topic of current HIV research. Whereas much attention has been placed on the clinical …

Identification of minority resistance mutations in the HIV-1 integrase coding region using next generation sequencing

J Fonager, JT Larsson, C Hussing, FN Engsig… - Journal of Clinical …, 2015 - Elsevier
Background The current widely applied standard method to screen for HIV-1 genotypic
resistance is based on Sanger population sequencing (Sseq), which does not allow for the …

High rates of drug resistance among newly diagnosed HIV-infected children in the national prevention of mother-to-child transmission program in Togo

M Salou, C Butel, AA Konou, DK Ekouevi… - The Pediatric …, 2016 - journals.lww.com
Background: Prevention of mother-to-child transmission (PMTCT) programs have been
largely scaled-up, but data on infant HIV drug resistance from PMTCT programs …

[HTML][HTML] Application of next generation sequencing in HIV drug resistance studies in Africa, 2005–2019: A systematic review

P Mathobo, ND Matume, PO Bessong - Scientific African, 2021 - Elsevier
The control of HIV transmission is a high priority for Africa, in line with Agenda 2063 of the
African Union. The development of HIV drug resistance poses a significant challenge in …

[PDF][PDF] Scientific African

P Mathobo, ND Matume, PO Bessong - 2021 - researchgate.net
abstract The control of HIV transmission is a high priority for Africa, in line with Agenda 2063
of the African Union. The development of HIV drug resistance poses a significant challenge …

[PDF][PDF] 1. Université de Lomé, Laboratoire de Biologie moléculaire et d'immunologie (BIOLIM/FSS/UL), Lomé, Togo 2. Université de Lomé, Département des sciences …

M Salou, C Butel, AA Konou, DK Ekouevi, N Vidal… - 2016 - academia.edu
Background: Prevention of mother-to-child transmission (PMTCT) programs have been
largely scaled-up, but data on infant HIV drug resistance from PMTCT programs …