Antimicrobial activity of natural and semi-synthetic carbazole alkaloids

YY Ding, H Zhou, BQ Zhang, ZJ Zhang… - European Journal of …, 2023 - Elsevier
Since the first natural carbazole alkaloid, murrayanine, was isolated from Mwraya Spreng,
carbazole alkaloid derivatives have been widely concerned for their anti-tumor, anti-viral …

[HTML][HTML] Carbazole derivatives as potential antimicrobial agents

SA Patil, SA Patil, EA Ble-González, SR Isbel… - Molecules, 2022 - mdpi.com
Microbial infection is a leading cause of death worldwide, resulting in around 1.2 million
deaths annually. Due to this, medicinal chemists are continuously searching for new or …

Novel D–π-A and A–π-D–π-A three-component photoinitiating systems based on carbazole/triphenylamino based chalcones and application in 3D and 4D printing

H Chen, G Noirbent, Y Zhang, D Brunel, D Gigmes… - Polymer …, 2020 - pubs.rsc.org
A series of carbazole or triphenylamine based mono-chalcones, displaying either D–π-A or
A–π-D–π-A architecture, have been designed and synthesized for intense absorption bands …

Carbazole scaffold in medicinal chemistry and natural products: a review from 2010-2015

LS Tsutsumi, D Gündisch, D Sun - Current Topics in Medicinal …, 2016 - ingentaconnect.com
9H-carbazole is an aromatic molecule that is tricyclic in nature, with two benzene rings fused
onto a 5-membered pyrrole ring. Obtained from natural sources or by synthetic routes, this …

Synthesis of extended conjugated indolyl chalcones as potent anti-breast cancer, anti-inflammatory and antioxidant agents

PS Bhale, HV Chavan, SB Dongare… - Bioorganic & medicinal …, 2017 - Elsevier
In the present investigation, synthesis of a series of extended conjugated δ-chloro-α-cyano
substituted indolyl chalcones (5a–p) was accomplished by reacting 3-cyanoacetylindole 2 …

Synthesis, anticancer and antioxidant properties of new indole and pyranoindole derivatives

D Iacopetta, A Catalano, J Ceramella, A Barbarossa… - Bioorganic …, 2020 - Elsevier
The indole scaffold has been recognized, over the years, as a model for the synthesis of
compounds with anticancer activity by dint of its substantiated ability to act via multiple …

Progress and development of carbazole scaffold based as potential anti-alzheimer agents using MTDL approach

N Kumar, P Gupta, S Bansal - Letters in Drug Design & …, 2022 - ingentaconnect.com
Alzheimer's is a neurodegenerative disease (NDs) found in old age people with associated
most common symptom dementia. MTDLs (Multi-Target Direct Ligand strategy) is based on …

Current perspective of natural alkaloid carbazole and its derivatives as antitumor agents

MS Shaikh, R Karpoormath, N Thapliyal… - Anti-Cancer Agents …, 2015 - ingentaconnect.com
Throughout our evolution, the importance of natural products for medicine and health has
been increasing and it continues to be a key source of novel anticancer drugs, leads and …

[HTML][HTML] Synthesis, in silico, and in vitro biological evaluation of new furan hybrid molecules

S Manolov, I Ivanov, D Bojilov, P Nedialkov - Processes, 2022 - mdpi.com
Herein, we report the synthesis of new hybrid molecules between furan and N-containing
heterocyclic compounds such as pyrrolidine, 1, 2, 3, 4-tetrahydroquinoline, 1, 2, 3, 4 …

[HTML][HTML] Advances in the Synthesis of Heteroaromatic Hybrid Chalcones

A Mallia, J Sloop - Molecules, 2023 - mdpi.com
Chalcones continue to occupy a venerated status as scaffolds for the construction of a
variety of heterocyclic molecules with medicinal and industrial properties. Syntheses of …