Accelerating antiviral drug discovery: lessons from COVID-19
During the coronavirus disease 2019 (COVID-19) pandemic, a wave of rapid and
collaborative drug discovery efforts took place in academia and industry, culminating in …
collaborative drug discovery efforts took place in academia and industry, culminating in …
[HTML][HTML] Remdesivir for the treatment of COVID‐19
F Grundeis, K Ansems, K Dahms… - … of systematic reviews, 2023 - ncbi.nlm.nih.gov
Background Remdesivir is an antiviral medicine approved for the treatment of mild‐to‐
moderate coronavirus disease 2019 (COVID‐19). This led to widespread implementation …
moderate coronavirus disease 2019 (COVID‐19). This led to widespread implementation …
Risk factors of severe COVID-19: a review of host, viral and environmental factors
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …
asymptomatic infections to severe disease and death. Understanding the risk factors of …
Rapid review and meta-analysis of serial intervals for SARS-CoV-2 Delta and Omicron variants
Background The serial interval is the period of time between symptom onset in the primary
case and symptom onset in the secondary case. Understanding the serial interval is …
case and symptom onset in the secondary case. Understanding the serial interval is …
Monkeypox infection among men who have sex with men: PCR testing on seminal fluids
AR Raccagni, C Candela, D Mileto, D Canetti… - The Journal of …, 2022 - ncbi.nlm.nih.gov
Fig. 1. Setting of the restaurant.(A) Floor plan;(B) image obtained from the video camera. out
both close contact and fomite routes. In this specific context, we found that close contact …
both close contact and fomite routes. In this specific context, we found that close contact …
Predicting severity in COVID-19 disease using sepsis blood gene expression signatures
Severely-afflicted COVID-19 patients can exhibit disease manifestations representative of
sepsis, including acute respiratory distress syndrome and multiple organ failure. We …
sepsis, including acute respiratory distress syndrome and multiple organ failure. We …
A systematic review and meta-analysis of the effectiveness and safety of COVID-19 vaccination in older adults
K Xu, Z Wang, M Qin, Y Gao, N Luo, W Xie… - Frontiers in …, 2023 - frontiersin.org
In the coronavirus disease 2019 (COVID-19) pandemic, vaccinations were essential in
preventing COVID-19 infections and related mortality in older adults. The objectives of this …
preventing COVID-19 infections and related mortality in older adults. The objectives of this …
[HTML][HTML] Ocular involvement in monkeypox: description of an unusual presentation during the current outbreak
V Mazzotta, A Mondi, F Carletti, F Baldini… - The Journal of …, 2022 - ncbi.nlm.nih.gov
Fig. 1. Setting of the restaurant.(A) Floor plan;(B) image obtained from the video camera. out
both close contact and fomite routes. In this specific context, we found that close contact …
both close contact and fomite routes. In this specific context, we found that close contact …
A population-scale temporal case–control evaluation of COVID-19 disease phenotype and related outcome rates in patients with cancer in England (UKCCP)
T Starkey, MC Ionescu, M Tilby, M Little, E Burke… - Scientific Reports, 2023 - nature.com
Patients with cancer are at increased risk of hospitalisation and mortality following severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, the SARS-CoV …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, the SARS-CoV …
Inhibition of the mitochondrial pyruvate carrier simultaneously mitigates hyperinflammation and hyperglycemia in COVID-19
The relationship between diabetes and coronavirus disease 2019 (COVID-19) is
bidirectional: Although individuals with diabetes and high blood glucose (hyperglycemia) …
bidirectional: Although individuals with diabetes and high blood glucose (hyperglycemia) …